Results 101 to 110 of about 36,655 (113)

<i>NPRL2</i> gene therapy induces effective antitumor immunity in <i>KRAS/STK11</i> mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model. [PDF]

Elife
Meraz IM, Majidi M, Song R, Meng F, Gao L, Wang Q, Wang J, Shpall EJ, Roth JA.   +8 more
europepmc   +1 more source

A nanoencapsulated oral formulation of fenretinide promotes local and metastatic breast cancer dormancy in HER2/neu transgenic mice. [PDF]

J Exp Clin Cancer Res
De Angelis ML, Francescangeli F, Aricò E, Verachi P, Zucchetti M, Matteo C, Petricci E, Pilozzi E, Orienti I, Boe A, Eramo A, Rossi R, Corati T, Macchia D, Pacca AM, Zeuner A, Baiocchi M.   +16 more
europepmc   +1 more source

Butterfly blues and greens caused by subtractive colour mixing of carotenoids and bile pigments. [PDF]

J Comp Physiol A Neuroethol Sens Neural Behav Physiol
Stavenga DG.
europepmc   +1 more source

Genome-wide association analysis identifies seven loci conferring resistance to multiple wheat foliar diseases, including yellow and brown rust resistance originating from Aegilops ventricosa

Gardner KA, Love B, Basler PB, Barber T, Berry S, Bird N, Borum F, Boyd L, Brown JK, Bryant R, Fenwick P, Feuerhelm D, Gosman N, Hayes C, Henriksson T, Jack P, Kirby R, Kerton M, Lage J, Nielsen LK, Rose G, Sharma R, Schondelmaier J, Smith S, Vallenback P, Warner D, Wright TI, Zanella CM, Cockram J, Mackay IJ, O’Sullivan DM.   +30 more
europepmc   +1 more source

Integrated metabolomics and transcriptomics reveal the potential of hydroxy-alpha-sanshool in alleviating insulin resistance. [PDF]

Mol Med
Zhu Y, Yang P, Ren T, Chen Z, Tian H, Wang M, Zhang C.   +6 more
europepmc   +1 more source

A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments. [PDF]

Nat Cell Biol
Chidley C, Darnell AM, Gaudio BL, Lien EC, Barbeau AM, Vander Heiden MG, Sorger PK.   +6 more
europepmc   +1 more source

Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH. [PDF]

Nucleic Acids Res
Weiss M, Hettrich S, Hofmann T, Hachim S, Günther S, Braun T, Boettger T.   +6 more
europepmc   +1 more source

A novel USP4 inhibitor that suppresses colorectal cancer stemness by promoting β-catenin and Twist1 degradation. [PDF]

J Transl Med
Li F, Zhou Y, Lin X, Zhang Y, Hu Q, Zhao E, Li H, Pan X, Shu F, Zhang K, Huang C, Tang N, Liao W.   +12 more
europepmc   +1 more source

PAX2 induces endometrial cancer by inhibiting mitochondrial function via the CD133-AKT1 pathway. [PDF]

Mol Cell Biochem
Hua F, Cai Y.
europepmc   +1 more source

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The mTOR/4E-BP1/eIF4E signalling pathway as source of cancer drug targets.

Current Medicinal Chemistry, 2022
The mechanistic/mammalian target of rapamycin (mTOR) is the crucial hub of signalling pathways that regulate essential steps in the cell life cycle. Once incorporated in the mTORC1 complex, mTOR phosphorylates the eukaryotic initiation factor 4E (eIF4E)-
C. Maracci, S. Motta, A. Romagnoli, Matteo Costantino, P. Perego, D. Di Marino   +5 more
semanticscholar   +1 more source