Results 101 to 110 of about 52,618 (178)

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, 2020
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core  

Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta cells.

, 2009
High-density lipoproteins (HDLs) protect pancreatic beta cells against apoptosis. This property might relate to the increased risk to develop diabetes in patients with low HDL blood levels.
Widmann, C., Poussin, C., Thorens, B., Ghosh, S., Mooser, V., Rütti, S., Yang, J.Y., Butty, A.C., Au, K., Bulat, N., Pétremand, J., Waeber, G.   +11 more
core   +1 more source

TOS Motif-Mediated Raptor Binding Regulates 4E-BP1 Multisite Phosphorylation and Function

, 2003
Background: The mammalian target of rapamycin, mTOR, is a serine/threonine kinase that controls cell growth and proliferation via the translation regulators eukaryotic initiation factor 4E (eIF4E) binding protein 1 (4E-BP1) and ribosomal protein S6 ...
Sabatini, David M., Blenis, John, Fingar, Diane C., Schalm, Stefanie S.   +3 more
core   +1 more source

UEG Week 2024 Moderated Posters

United European Gastroenterology Journal, Volume 12, Issue S8, Page 201-664, October 2024.
wiley   +1 more source

Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells

, 2001
Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells.BackgroundAugmented protein translation by insulin involves activation of eukaryotic initiation factor 4E (eIF4E) that follows release of ...
Gingras, Anne-Claude, Abboud, Hanna E., Feliers, Denis, Choudhury, Goutam Ghosh, Kasinath, Balakuntalam S., Sonenberg, Nahum, Stewart, Jennifer L., Bhandari, Basant K., Duraisamy, Senthil   +8 more
core   +1 more source

Exogenous expression of 4E-BP1 or 4E-BP2 in respective 4E-BP1^−/− or 4E-BP2^−/− MEFs increases susceptibility to VSV infection.

, 2014
(A) 4E-BP1−/− and 4E-BP2−/− MEFs were transduced with retroviruses carrying an empty vector (control), or retroviruses expressing either 4E-BP1 or 4E-BP2.
Polen Sean (677995), Izzar Linares (677996), Maritza Jaramillo (259910), Atef Nehdi (13719), Rodney Colina (677997), Tommy Alain (414354)   +5 more
core   +1 more source

A review of the cognitive impact of neurodevelopmental and neuropsychiatric associated copy number variants. [PDF]

Transl Psychiatry, 2023
Molloy CJ, Quigley C, McNicholas Á, Lisanti L, Gallagher L.   +4 more
europepmc   +1 more source

Control of 4E-BP1 expression in mouse brown adipose tissue by the β3-adrenoceptor

, 2004
Knockout of the translation inhibitor 4E-BP1 induces an overexpression of uncoupling protein-1 (UCP1) [Nature Medicine 7 (2001) 1128]. A possible inverse control of UCP1 and 4E-BP1 expressions in mouse brown adipose tissue was investigated. Cold-exposure,
Kuehne, Françoise, Arboit, Patrizia, Giacobino, Jean-Paul, Lehr, Lorenz, Muzzin, Patrick, Jimenez, Maria, Poulin, Francis   +6 more
core   +1 more source

Increased 4E-BP1 Expression Protects against Diet-Induced Obesity and Insulin Resistance in Male Mice

, 2016
SummaryObesity is a major risk factor driving the global type II diabetes pandemic. However, the molecular factors linking obesity to disease remain to be elucidated. Gender differences are apparent in humans and are also observed in murine models. Here,
Albert R. La Spada, Viray, Christian Michael, Rodriguez, Ariana A., Del Greco, Elizabeth, Sitzmann, Joanna M., Lizbeth Leon Martinez, Ariana A. Rodriguez, Carr, Kaili Lia, Christian Michael Viray, Academia, Emmeline C., Somasish G. Dastidar, Travis D. Ashe, Joanna M. Sitzmann, Martinez, Lizbeth Leon, Shih-Yin Tsai, Kaili Lia Carr, Brian Stephen Kaplowitz, Brian K. Kennedy, Kaplowitz, Brian Stephen, La Spada, Albert R., Emmeline C. Academia, Tsai, Shih-Yin, Elizabeth Del Greco, Dastidar, Somasish G., Ashe, Travis D., Kennedy, Brian K.   +25 more
core   +1 more source

Phosphorylation of 4E-BP1 by LRRK2 in vitro and in mammalian cells.

, 2013
(A) In vitro kinase assay with [32P]-γ-ATP, recombinant GST-tagged human LRRK2 (ΔN, residues 970–2527) and GST-tagged human 4E-BP1. Coomassie-stained SDS-PAGE gels indicate equal loading of 4E-BP1 and LRRK2 proteins in each condition.
Adamantios Mamais (302600), Darren J. Moore (154952), Liliane Glauser (154950), Klodjan Stafa (154945), Philip J. Webber (185205), Elpida Tsika (302602), Andrew B. West (185211), Rina Bandopadhyay (302603), Alzbeta Trancikova (154943)   +8 more
core   +1 more source