Results 81 to 90 of about 49,552 (162)

Mitosis-related phosphorylation of the eukaryotic translation suppressor 4E-BP1 and its interaction with eukaryotic translation initiation factor 4E (eIF4E)

open access: yesJournal of Biological Chemistry, 2019
Eukaryotic translation initiation factor 4E (eIF4E)–binding protein 1 (4E-BP1) inhibits cap-dependent translation in eukaryotes by competing with eIF4G for an interaction with eIF4E.
Rui Sun   +4 more
semanticscholar   +1 more source

4E‐BP1 and 4E‐BP2 double knockout mice are protected from aging‐associated sarcopenia

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2019
Sarcopenia is the loss of muscle mass/function that occurs during the aging process. The links between mechanistic target of rapamycin (mTOR) activity and muscle development are largely documented, but the role of its downstream targets in the ...
O. Le Bacquer   +12 more
semanticscholar   +1 more source

Polymetamorphism during the Grenvillian Orogeny in SE Ontario: Results from trace element mapping, in situ geochronology, and diffusion geospeedometry

open access: yesJournal of Metamorphic Geology, Volume 42, Issue 1, Page 35-61, January 2024.
Abstract The Flinton Group is a metasedimentary succession of the Grenville Province in SE Ontario, potentially allowing insight into the tectono‐thermal evolution of continental crust during the Mesoproterozoic. At its Green Bay locality, Flinton Group metapelites of the staurolite zone contain abundant, post‐kinematic garnet porphyroblasts.
F. Gaidies   +6 more
wiley   +1 more source

Translational repression of Ccl5 and Cxcl10 by 4E‐BP1 and 4E‐BP2 restrains the ability of mouse macrophages to induce migration of activated T cells

open access: yesEuropean Journal of Immunology, 2019
Signaling through the mechanistic target of rapamycin complex 1 (mTORC1) is a major regulatory node of pro‐inflammatory mediator production by macrophages (MΦs).
M. William   +5 more
semanticscholar   +1 more source

Advancements in B‐Cell Non‐Hodgkin’s Lymphoma: From Signaling Pathways to Targeted Therapies

open access: yesAdvances in Hematology, Volume 2024, Issue 1, 2024.
Lymphoma is the sixth most prevalent cancer globally. Non‐Hodgkin’s lymphomas are the majority group of lymphomas, with B cells accounting for approximately 95% of these lymphomas. A key feature of B‐cell lymphoma is the functional perturbations of essential biological pathways caused by genetic aberrations.
Abdullah Alfaifi   +9 more
wiley   +1 more source

PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target

open access: yesVirulence, 2017
Rotavirus infection is a major cause of severe dehydrating diarrhea in infants younger than 5 y old and in particular cases of immunocompromised patients irrespective to the age of the patients. Although vaccines have been developed, antiviral therapy is
Yuebang Yin   +11 more
semanticscholar   +1 more source

ORIENTALIS DAN DUPLIKASI BAHASA ALQURAN (Telaah dan Sanggahan atas Karya Christoph Luxenberg)

open access: yesHunafa: Jurnal Studia Islamika, 2012
The Qur’an is a holy book seving as the source of inspiration for the seekers of science, including those who belong to orientalists. They make Alquran as an object of study and research among both academic and non-academic.
Khaeruddin Yusuf
doaj  

امام جلال الدین السیوطیؒ کی تفسیر الدرالمنثور فی التفسیر الماثور میں اشعار عرب سے استشہاد کا علمی جائزہ۔A view of cross-referencing from Arabic poetry in Tafseer Ad-dur-ul- Mansoor by Sayooti

open access: yesالإيضاح, 2013
"This paper describes that if we want to know about poetry we must understand that out of context we can never arrive at our destination. The Quran should be read and understood in totality of its message and spirit. Its verses are local and universal.
ڈاکٹر عرفان اللہ
doaj  

Magnesium Supplement and the 15q11.2 BP1–BP2 Microdeletion (Burnside–Butler) Syndrome: A Potential Treatment?

open access: yesInternational Journal of Molecular Sciences, 2019
The 15q11.2 BP1–BP2 microdeletion (Burnside–Butler) syndrome is an emerging disorder that encompasses four genes (NIPA1, NIPA2, CYFIP1, and TUBGCP5).
M. Butler
semanticscholar   +1 more source

Islamic Education with the help of Information Technology: Advantages and Disadvantages

open access: yesThe Islamic Culture, 2019
One of the most important function of tranferring religious beliefs and teaching to the younger generation was performed by schools as well as parents and elder family members.
Sheikh Adnan Ahmed Usmani, Hina Tabassum
doaj  

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