Results 91 to 100 of about 5,159 (241)

Bisphenol A causes reproductive toxicity, decreasesdnmt1transcription, and reduces global DNA methylation in breeding zebrafish(Danio rerio) [PDF]

, 2016
Bisphenol A (BPA) is a commercially important high production chemical widely used in epoxy resins and polycarbonate plastics, and is ubiquitous in the environment. Previous studies demonstrated that BPA activates estrogenic signaling pathways associated
Bates D, E. L. Dempster, E. M. Santos, Eklund A, G. C. Paull, Head JA, J. Mill, J. Viana, L. A. Trunkfield, L. V. Laing, M. Trznadel, R. J. Wilson, R. van Aerle, T. M. Uren Webster, Turek-Plewa J, Vincent QV, Warnes GR   +16 more
core   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

Angewandte Chemie International Edition, EarlyView.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +1 more source

Metabolomic modulations of HepG2 cells exposed to bisphenol analogues

Environment International, 2019
Bisphenol analogues including bisphenol A (BPA), bisphenol AF (BPAF), bisphenol F (BPF), and bisphenol S (BPS) share similar chemical structures and endocrine disrupting effects.
Siqing Yue, Jie Yu, Yuan Kong, Haofeng Chen, Manfei Mao, Chenyang Ji, Shuai Shao, Jianqiang Zhu, Jinping Gu, Meirong Zhao   +9 more
doaj   +1 more source

Evaluating the Effects of Bisphenols F and S with Respect to Bisphenol A on Primordial Germ Cell Migration in Zebrafish (Danio rerio) Embryos Using Immunofluorescence Microscopy [PDF]

, 2019
Primordial Germ Cell (PGC) migration occurs in early embryonic development and is highly conserved across taxa. PGC migration occurs within the first 24 hours post fertilization (hpf) in zebrafish, making the organism an efficient model for observing the
Freeman, Edward A., Roba, George, Safura, Siti Sarah   +2 more
core   +1 more source

"Stockpile" of slight transcriptomic changes determines the indirect genotoxicity of low-dose BPA in thyroid cells [PDF]

, 2016
Epidemiological and experimental data highlighted the thyroid-disrupting activity of bisphenol A (BPA). Although pivotal to identify the mechanisms of toxicity, direct low-dose BPA effects on thyrocytes have not been assessed. Here, we report the results
Altucci, Lucia, Ambrosino, Concetta, Amendola, Elena, Ceccarelli, Michele, Cuomo, Danila, D'Angelo, Fulvio, De Felice, Mario, Mallardo, Massimo, Nebbioso, Angela, Porreca, Immacolata, Ulloa Severino, Luisa   +10 more
core   +4 more sources

Subterranean environments contribute to three‐quarters of classified ecosystem services

Biological Reviews, EarlyView.
ABSTRACT Beneath the Earth's surface lies a network of interconnected caves, voids, and systems of fissures forming in rocks of sedimentary, igneous, or metamorphic origin. Although largely inaccessible to humans, this hidden realm supports and regulates services critical to ecological health and human well‐being.
Stefano Mammola, David Brankovits, Tiziana Di Lorenzo, Isabel R. Amorim, Raluca Ioana Bancila, Adrià Bellvert, Enrico Bernard, Anna Blomberg, Paulo A.V. Borges, Martina Cappelletti, Rodrigo Lopes Ferreira, Rosalina Gabriel, Diana M. P. Galassi, Laura Garzoli, Vasilis Gerovasileiou, Grant C. Hose, Kathryn L. Korbel, Simone Martino, Ana Z Miller, Nataša Mori, Veronica Nanni, Giuseppe Nicolosi, Mattia Saccò, Troy S. Sakihara, Marconi Souza Silva, Anne E. Tamalavage, Maja Zagmajster, Efraín Chávez, Christian Griebler, Pedro Cardoso, Alejandro Martínez   +30 more
wiley   +1 more source

Computational study suggesting reconsideration of BPA analogues based on their endocrine disrupting potential estimated by binding affinities to nuclear receptors

Ecotoxicology and Environmental Safety, 2019
Due to its endocrine disrupting nature Bisphenol-A (BPA), a chemical used in the plastic industry was placed under a ban which provided an incentive for its replacement by bisphenol and non-bisphenol based plasticizers. The use of bisphenol replacements in industry is increasing day by day. Therefore, it becomes prudent to put them under scrutiny.
Afia, Usman, Masood, Ahmad
openaire   +2 more sources

Zebrafish Embryonic Exposure to BPAP and Its Relatively Weak Thyroid Hormone-Disrupting Effects

Toxics, 2020
Safe endocrine-disrupting alternatives for bisphenol A (BPA) are needed because its adverse health effects have become a public concern. Some bisphenol analogues (bisphenol F and S) have been applied, but their endocrine-disrupting potential is either ...
Sangwoo Lee, Kojo Eghan, Jieon Lee, Donggon Yoo, Seokjoo Yoon, Woo-Keun Kim   +5 more
doaj   +1 more source

Bisphenol A, S or F mother’s dermal impregnation impairs offspring immune responses in a dose and sex-specific manner in mice

Scientific Reports, 2021
Bisphenol (BP)A is an endocrine disruptor (ED) widely used in thermal papers. Regulatory restrictions have been established to prevent risks for human health, leading to BPA substitution by structural analogues, like BPS and BPF.
Yann Malaisé, Corinne Lencina, Christel Cartier, Maïwenn Olier, Sandrine Ménard, Laurence Guzylack-Piriou   +5 more
doaj   +1 more source

Pesticide Contamination in the Hair of Children From Colonia San Juan, a Rural Community in Paraguay

Drug Testing and Analysis, EarlyView.
Hair analysis in children from a rural community in Paraguay reveals exposure to organophosphates, pyrethroids, neonicotinoids, fungicides, herbicides, and endocrine disruptors, highlighting the urgent need for stricter environmental protections and preventive health measures. ABSTRACT Chronic exposure to pesticides can cause carcinogenic, reproductive,
Stela Benitez Leite, Alba Iglesias‐Gonzalez, Mirta Noemí Mesquita, María Luisa Macchi, Robin Mesnage, Brice M. R. Appenzeller   +5 more
wiley   +1 more source