Results 61 to 70 of about 1,619 (158)

Developmental effects and lipid disturbances of zebrafish embryos exposed to three newly recognized bisphenol A analogues

Environment International
Bisphenol G (BPG), bisphenol M (BPM) and bisphenol TMC (BPTMC), are newly recognized analogues of bisphenol A (BPA), which have been detected in multiple environmental media. However, the understanding of their negative impacts on environmental health is
Xiaoyu Zhao, Zaiteng Liu, Yining Zhang, Yecan Pan, Tiancai Wang, Zishuang Wang, Zishu Li, Qingxiao Zeng, Yongzhong Qian, Jing Qiu, Xiyan Mu   +10 more
doaj   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

Zebrafish Embryonic Exposure to BPAP and Its Relatively Weak Thyroid Hormone-Disrupting Effects

Toxics, 2020
Safe endocrine-disrupting alternatives for bisphenol A (BPA) are needed because its adverse health effects have become a public concern. Some bisphenol analogues (bisphenol F and S) have been applied, but their endocrine-disrupting potential is either ...
Sangwoo Lee, Kojo Eghan, Jieon Lee, Donggon Yoo, Seokjoo Yoon, Woo-Keun Kim   +5 more
doaj   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

Unravelling immunomodulatory effects of bisphenol A substitutes on human macrophages, T and B lymphocytes using in vitro models

Ecotoxicology and Environmental Safety
This study investigates the immunomodulatory effects of BPA substitutes using in silico and in vitro approaches. A comprehensive in silico screening with Endocrine Disruptome of BPA and its 25 substitutes revealed that BPG, BPS-MAE, BPS-MPE, BPPH and ...
Nina Franko, Tijana Markovič, Pia Žižek, Anja Kodila, Irena Mlinarič Raščan, Marija Sollner Dolenc   +5 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source

Environmental triggers of autoimmunity: The association between bisphenol analogues and systemic lupus erythematosus

Ecotoxicology and Environmental Safety
The aim of this research was to examine the correlation between the exposure to bisphenol analogues (BPs), such as bisphenol A (BPA), bisphenol F (BPF), and bisphenol S (BPS), and the risk of developing systemic lupus erythematosus (SLE).
Yiyu Wang, Hong Wu, Kaidi Li, Ronggui Huang, Jiamin Liu, Zhangwei Lu, Yiyuan Wang, Jing Wang, Yujie Du, Xue Jin, Ya Xu, Baozhu Li   +11 more
doaj   +1 more source

Thermoresistive Sensors Based on Eco‐Friendly Carbon Dioxide‐Derived Polymeric Poly(Cyclohexene)carbonate Loaded With Reduced Graphene Oxide and Carbon Black

Polymer Engineering &Science, EarlyView.
Thermoresistive sensing materials derived from eco‐friendly polymers for broad‐range temperature measurements. ABSTRACT Carbon dioxide‐derived polycarbonates (CO2‐PCs) present a sustainable alternative to standard bisphenol A polycarbonates (BPA‐PCs), as they are synthesized from the reaction between epoxide and carbon dioxide (CO2). In fact, these eco‐
Ane Martín‐Ayerdi, Luis Rubio‐Peña, Nikola Peřinka, Sergio Merillas, Itziar Oyarzabal, José Luis Vilas‐Vilela, Pedro Costa, Senentxu Lanceros‐Méndez   +7 more
wiley   +1 more source

Coupled observation‐operator approximations in outer‐loop coupling data assimilation

Quarterly Journal of the Royal Meteorological Society, EarlyView.
We present a methodology for coupled variational data assimilation that allows the effect of coupled observation operators whilst maintaining separate minimisations across model components. This allows us to constrain the atmosphere, ocean, and sea‐ice components of our coupled model directly from satellite radiances. We illustrate the system in action
P. A. Browne, P. de Rosnay, A. J. Geer, S. Quesada‐Ruiz, T. Scanlon, E. Villeneuve   +5 more
wiley   +1 more source