Isolation of a Divergent Strain of Bovine Parainfluenza Virus Type 3 (BPIV3) Infecting Cattle in China [PDF]
Bovine parainfluenza virus type 3 (BPIV3) is one of the most important known viral respiratory pathogens of both young and adult cattle. It is also named “heat stress in transport”, causing morbidity and mass death. New variants of BPIV3 have
Elcio Leal +2 more
exaly +5 more sources
A Comparative Study of the Effects of Al(OH)3 and AlPO4 Adjuvants on the Production of Neutralizing Antibodies (NAbs) against Bovine parainfluenza Virus Type 3 (BPIV3) in Guinea Pigs [PDF]
Aluminum-containing adjuvants are extensively used for inactive human and animal vaccines owing to their favorable immunostimulative and safe properties.
R Heidary +4 more
exaly +2 more sources
Protective efficacy of a recombinant adenovirus expressing novel dual F and HN proteins of bovine parainfluenza virus type 3 [PDF]
Bovine parainfluenza virus type 3 (BPIV3) is a viral respiratory pathogen that infects cattle and causes significant economic losses. We generated a recombinant adenovirus called rHAd5-F + HN by expressing the fusion (F) and hemagglutinin-neuraminidase ...
Jiaqi Zhang +13 more
doaj +2 more sources
Multi-Epitope-Based Peptide Vaccine Against Bovine Parainfluenza Virus Type 3: Design and Immunoinformatics Approach [PDF]
Bovine parainfluenza virus type 3 (BPIV3) is a significant pathogen implicated in bovine respiratory disease complex (BRDC), leading to lung tissue destruction, immunosuppression, and subsequent bacterial infections in cattle, hence incurring ...
Junbo Wang +8 more
doaj +2 more sources
Construction and characterization of a reverse genetics system of bovine parainfluenza virus type 3c as a tool for rapid screening of antivirals in vitro [PDF]
Bovine parainfluenza virus type 3 (BPIV3) is a key pathogen associated with bovine respiratory disease complex (BRDC). However, its specific pathogenesis mechanisms have not been fully elucidated.
Yu Han +10 more
doaj +2 more sources
Intranasal bovine/human parainfluenza virus 3 vaccine candidates expressing human metapneumovirus wild-type or pre-fusion F protein elicit protective immunity against human metapneumovirus in hamsters [PDF]
Human metapneumovirus (HMPV) and human parainfluenza virus 3 (HPIV3) are among the leading causes of severe pediatric respiratory illness worldwide, and there are no licensed vaccines.
Sirle Saul +9 more
doaj +2 more sources
Blocking virus infection with BacMam virus delivery bovine interferon-α gene [PDF]
Interferon-αs (IFN-αs) are crucial cytokines for inducing protective antiviral responses. The baculovirus-mediated gene transduction of mammalian cells (BacMam) is an efficient delivery tool for recombinant protein expression in mammalian cells.
Zhenying Fan +9 more
doaj +2 more sources
Paramyxovirus matrix protein redirects METTL3 for dual regulation of viral replication and immune evasion. [PDF]
N6-methyladenosine (m6A) epitranscriptomic modifications play crucial roles in regulating both host and viral gene expression. Here, we revealed a novel mechanism by which paramyxoviruses exploit host m6A machinery to simultaneously enhance viral ...
Takashi Okura +15 more
doaj +2 more sources
Bovine respiratory disease complex (BRDC) occurs widely in cattle farms. The main viral pathogens include bovine viral diarrhea virus (BVDV), Bovine herpesvirus 1 (BoHV-1), bovine parainfluenza virus type 3 (BPIV3), and bovine respiratory syncytial virus
Xin Yin
exaly +3 more sources
Identification of Risk Factors Associated with Treatment for BRD in Beef Calves Within the First 60 Days After Arrival at Fattening Operations in Northwestern Italy Beef Calves [PDF]
Bovine respiratory disease (BRD) impacts beef cattle health and farming systems. To better understand the BRD predisposing factors, a study was conducted in northwest Italy on a population of 26 batches (760 animals) of beef cattle imported from France ...
Isabella Nicola +5 more
doaj +2 more sources

