Results 71 to 80 of about 102,336 (308)

Happiness and air quality: microdata analysis in Indonesia

open access: yesJournal of Health, Population and Nutrition
Background While economics is growing in Indonesia, its Happiness Index remains steady. Regarding the average concentration of dissolved particles, Indonesia is ranked sixth globally. Many factors can affect happiness.
Novilya Limayani, Erwin Tanur
doaj   +1 more source

A Rare Case of Compound Heterozygous Sickle Cell Beta Thalassaemia with High HbF and Normal HbA2 Levels Detected on HPLC [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Compound heterozygous Sickle Haemoglobin (HbS) beta (β) thalassaemia arises from the mutations associated with sickle cell and β thalassaemia and significantly affects populations in low income countries like India.
Ruchi Agarwal   +4 more
doaj   +1 more source

The $BP^*$-module structure of $BP^*(E_8)$ for $p=3$ [PDF]

open access: yesPublicacions Matemàtiques, 1984
Letting \(BP^*(-)\) denote Brown-Peterson cohomology at the prime \(p=3\), the author computes the \(BP^*\)-module structure of \(BP^*(E_ 7)\) and \(BP^*(E_ 8)\). This is a hard problem, requiring previous calculations by various authors of the integral and mod 3 cohomology and K-theory of \(E_ 7\) and \(E_ 8\), as well as their mod 3 BP-cohomology ...
openaire   +3 more sources

Patellar Tendon Revision Reconstruction Using Transosseous Patella All‐Suture Anchors, Semitendinosus Autograft, and Achilles Allograft

open access: yesArthroscopy Techniques, EarlyView.
Abstract Patellar tendon rupture is an uncommon but highly treatable injury, with excellent repair outcomes and low reoperation rates. Chronic patellar tendon ruptures or repair failures pose a clinical challenge, but the success rates of reconstruction with extensor mechanism allograft or autograft are reported to be high in the literature. Still, the
Brett P. Salazar   +3 more
wiley   +1 more source

The integration of the British Pharmacological Society's prescription safety assessment into the WHO 6‐step model of rational pharmacotherapy in a Turkish medical school

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims At Koç University School of Medicine, a one‐week rational pharmacotherapy (RPHM) programme, modelled after WHO 6‐step, has been introduced in the fourth‐year curriculum to improve prescription skills. For efficient problem‐based learning (PBL) sessions on a prespecified topic, students need to brush up on basic pharmacology knowledge, so we ...
Sinem Ezgi Gülmez   +2 more
wiley   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk   +5 more
wiley   +1 more source

Market Proximity Agrarian Solidarity and Forest Fringe Institutions Shaping Household Resilience in Rural Poverty Contexts

open access: yesFuture Space
While poverty is often measured economically, its spatial dimension how location dictates survival strategies remains under-explored. This study analyzes how spatial context influences social interaction patterns among economically vulnerable households
Nanda Andi Purnamansyah, Arini Ismiati
doaj   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

Optimal dosing for vascular anomalies paediatric patients with population pharmacokinetic model of sirolimus

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Sirolimus is currently used off‐label for paediatric patients with vascular anomalies. However, the optimal dosage regimen for paediatric patients remains controversial. This study aimed to determine the optimal dosing regimen of sirolimus in these patients using a population pharmacokinetic (PK) model.
Seongmee Jeong   +13 more
wiley   +1 more source

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen   +14 more
wiley   +1 more source

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