Results 31 to 40 of about 1,858,753 (236)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

EFFECTIVENESS OF PARTICIPATION FUND OF THE STATES AND THE FEDERAL DISTRICT TO PROMOTE SOCIOECONOMIC BALANCE IN BRAZIL: an empirical analysis for the period 1993-2013

Economia & Região, 2018
To promote the socio-economic balance among the Brazilian states, the Federal Constitution determined that apportionment of the Participation Fund of the States and the Federal District - FPE - should benefit the less-favored regions.
Miriam Borges dos Santos, Danilo Soares Monte-mor, Neyla Tardin   +2 more
doaj   +1 more source

FORMAL EMPLOYMENT IN AGRICULTURE IN THE STATE OF PARANÁ: A gender analysis

Economia & Região, 2020
The present study analyzes the turnover and growth of formal employment in agriculture and its distribution to the microregions of Paraná from 2008 to 2016.
Josineide Aquino da Silva Amaral, Karla Cristina Tyskowski Teodoro Rodrigues, Jefferson Andronio Ramundo Staduto   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Lidocaine and remifentanil for ventricular tachycardia suppression in a dog: A case report

Open Veterinary Journal
Background: Ventricular tachycardia is an arrhythmia that, if not corrected, can lead to reduced ischemic stroke volume and cardiac output, resulting in low tissue perfusion.
Alyssa Brum de Souza Pahim, Giovana Copetti Jung, Talita Freitas Alves, Maria Eduarda de Moraes Guerra, Cristiana Teixeira da Silva, Gabriele Marques Lopes, Maria Lígia de Arruda Mestieri, Joao Pedro Scussel Feranti, Marília Teresa de Oliveira   +8 more
doaj   +1 more source

Composição de plantas invasoras em diferentes sistemas integrados de produção agropecuária

Agropecuária Catarinense, 2021
No âmbito global se reconhece o potencial dos sistemas integrados como uma via sustentável para alimentar nove bilhões de pessoas em 2050. Esses sistemas são capazes de incrementar a resiliência ambiental pelo aumento da diversidade biológica e pela ...
Daniel de Queiroz Barbosa, Anibal Moraes, Claudete Reisdorfer Lang, Leandro Bittencourt Oliveira, João Pedro Tavares Fernandes, Camila Crestani   +5 more
doaj