Brace Treatment Is Associated with Lower Curve Progression in Moderate Adolescent Idiopathic Scoliosis, While Psychosocial Outcomes Are Driven by Depressive Symptoms and Curve Progression. [PDF]
Keskin A +5 more
europepmc +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Dissecting morphological changes during floral abscission in <i>Arabidopsis thaliana</i>. [PDF]
Osahan R, Hoffmann N, Hepworth SR.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Shoulder-wearable soft robot for assisting older adults in scapular stretching. [PDF]
Isobe K +5 more
europepmc +1 more source
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Rehabilitation Protocols Following Patellar Instability Surgery: A Structured Review of Published Recommendations and AI Generated Guidance. [PDF]
Vidra M +7 more
europepmc +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Longitudinal quantitative T2 mapping and SPECT-CT assessment of unloading therapy within a randomized controlled trial for medial knee osteoarthritis. [PDF]
Verschueren J +7 more
europepmc +1 more source

