Results 181 to 190 of about 36,240 (264)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Tele-scoliosis-screening and treat protocol: A hybrid in-person and online approach for scoliosis treatment in remote patients. [PDF]

World J Methodol
Karavidas N, Tzatzaliaris D.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Carbon-halogen bond substitution enables high-utilization four-electron iodine redox in noncorrosive dilute electrolytes. [PDF]

Nat Commun
Shi Z, Tang Y, Wei Y, Liu G, Huang H, Qi J, Feng Z, Ye M, Zhang Y, Wen Z, Liu X, Yang Q, Zhi C, Li CC.   +13 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Pearls and Pitfalls of Ponseti Method Bracing for Idiopathic Clubfoot-An Institutional Guide to Optimize Orthotic Management. [PDF]

J Pediatr Soc North Am
Scher EM, Math D, Beber SA, Tse A, Williams CJ, Scher DM, Doyle SM.   +6 more
europepmc   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Optimising COVID-19 episode identification using serology and PCR/rapid antigen testing: insights from the BRACE trial. [PDF]

BMC Infect Dis
McDonald E, Pittet LF, Bonten M, Byrne A, Campbell J, Croda J, Dalcolmo M, Davidson AJ, Dos Santos G, Gardiner K, Gwee A, Jardim B, Lacerda M, Lucas M, Lynn DJ, Manning L, Marshall H, Perrett KP, Prat-Aymerich C, Puga MAM, Richmond P, Rodríguez-Baño J, Wadia U, Warris A, Wood N, Curtis N, Messina NL, BRACE Trial Consortium Group.   +27 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

The Impact of a Lightweight Pneumatic Robotic Knee Wearable on Gait. [PDF]

Case Rep Orthop
Lee JJ, Lyons S, Arora P, Morgan JJ, Chan S, Amanatullah DF.   +5 more
europepmc   +1 more source