Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Anterior Cruciate Ligament Repair With Internal Bracing Augmentation. [PDF]
Vadhera AS +8 more
europepmc +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
How the curve morphology differs between curve types in patients with adolescent idiopathic scoliosis during brace treatment? [PDF]
Cheung WK, Cheung PWH, Cheung JPY.
europepmc +1 more source
The effects of a semi‐rigid ankle brace on a simulated isolated subtalar joint instability [PDF]
Julie Choisne +4 more
openalex +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Comparison of clinical outcomes between plastic braces versus sponge abduction packs in the early rehabilitation period after rotator cuff repair. [PDF]
Du R +6 more
europepmc +1 more source
STEENBEEK FOOT ABDUCTION BRACE FOR CLUBFOOT: COST EFFECTIVE BUT IS IT EFFECTIVE? A PROSPECTIVE STUDY
Thatikonda Sai Dinesh, Prem Kotian
openalex +2 more sources
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Augmented Tendon Repair with Internal Bracing: Surgical Technique. [PDF]
Handzewniak N +6 more
europepmc +1 more source

