Results 81 to 90 of about 346,472 (343)

To brace or not to brace? : positive and negative effects of knee braces

open access: yes, 2019
Prophylactic knee braces are used in rehabilitation after surgery or during sports and are claimed to protect the knee from unphysiological loads. In this work, the effect of prophylactic knee braces on the knee was investigated to answer the question, if braces do really protect the knee or might even have negative side effects.
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Influence of miRNA on brace root patterning in Zea mays L. [PDF]

open access: yes, 2008
only availableBrace roots reduce lodging by providing support and represent the majority of the root system in adult plants. Previous quantitative trait locus mapping results showed that Teopod1 (Tp1), Teopod2 (Tp2), and Corngrass1 (Cg1), all mapped in ...
Davis, Georgia L.   +3 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Electronic monitoring of orthopedic brace compliance

open access: yesJournal of Children's Orthopaedics, 2015
Purpose Brace compliance measurement in adolescent idiopathic scoliosis (AIS) has been the subject of a few recent studies. Various sensors have been developed to measure compliance.
Tariq Rahman   +8 more
doaj   +1 more source

Automated beam builder [PDF]

open access: yes, 1980
Requirements for the space fabrication of large space structures are considered with emphasis on the design, development, manufacture, and testing of a machine which automatically produces a basic building block aluminum beam.
Muench, W. K.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

An Assessment of the Impact of Climate Change on Human Health in New Hampshire [PDF]

open access: yes, 2014
Climate change threatens human health in many ways. The negative impacts of climate change on human health are likely to increase in both magnitude and frequency as the climate continues to change in response to ever increasing global emissions of heat ...
Aytur, Semra   +2 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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