Results 81 to 90 of about 25,846 (308)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Braces minimais e suas propriedades
, 2021 McCuaig proved a generation theorem for braces, and used it as the principal induction tool to obtain a structural characterization of Pfaffian braces. A brace is minimal if deleting any edge results in a graph that is not a brace. From McCuaig’s brace
Phelipe Araujo Fabres
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
, 2010 Pair of men's braces in webbing and leather - from the The Betty Smithers Design Collection at Staffordshire University.
The Betty Smithers Design Collection at Staffordshire University +1 more
core
Semi-braces and the Yang-Baxter equation
, 2017 In this paper we obtain new solutions of the Yang-Baxter equation that are left non-degenerate throught left semi-braces, a generalization of braces introduced by Rump.
Ilaria Colazzo +5 more
core +1 more source
Evaluation of Perceived Acceptability, Beauty and Value of Different Orthodontic Brackets
Journal of Dental Biomaterial, 2015 Statement of Problem: Although different types of aesthetic brackets are introduced to orthodontic profession to reduce the complaints about the metallic braces, little studies have been done to assess patient's views regarding the attractiveness and ...
Moshkelgosha V, Salahi M, Rostami Sh
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Matched pairs and Yetter-Drinfeld braces [PDF]
It is proven that a matched pair of actions on a Hopf algebra H is equivalent to the datum of a Yetter–Drinfeld brace, which is a novel structure generalising Hopf braces.
Ferri Davide, Sciandra Andrea
core +3 more sources
Physical Therapy KoreaBackground: Using wearable passive back-support exoskeletons in workplace has attracted attention as devices that support the posture of workers, enhance their physical capabilities, and reduce physical risk factors.
Hee-Eun Ahn, Tae-Lim Yoon
doaj +1 more source