Results 81 to 90 of about 123,103 (378)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Directed cycle double covers: structure and generation of hexagon graphs [PDF]
, 2013 Jaeger's directed cycle double cover conjecture can be formulated as a problem of existence of special perfect matchings in a class of graphs that we call hexagon graphs. In this work, we explore the structure of hexagon graphs.
Jiménez, Andrea +2 more
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Youth Perception of Different Orthodontic Appliances
Patient Preference and Adherence, 2020 Reem A Alansari Department of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Reem A AlansariDepartment of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi ArabiaEmail ...
Alansari RA
doaj
Convergências - Revista de Investigação e Ensino das Artes, 2020 As instruções de segurança obrigatoriamente presentes nas bolsas dos assentos de todos os aviões comerciais, pelo seu grafismo, assumiram um estatuto icónico associado à viagem aérea. Desenvolvemos a hipótese de que as suas ilustrações, espectavelmente instrutivas e precisas, construíram um discurso visual que extravasou a mera cultura aeronáutica ...
openaire +1 more source
Incidence of white spot lesions among patients treated with clear aligners and traditional braces.
Angle Orthodontist, 2019 OBJECTIVES To compare the incidence of white spot lesions (WSLs) among patients treated with aligners and those treated with traditional braces. MATERIALS AND METHODS A group of 244 aligner patients (30.4 ± 14 years) was compared to a group of 206 ...
P. Buschang +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Lightweight orthotic braces [PDF]
, 1975 Leg brace is constructed of fiber-reinforced polymer material.
Baucom, R. M. +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source