The exposed proteomes of Brachyspira hyodysenteriae and B. pilosicoli. [PDF]
B. hyodysenteriae and B. pilosicoli are well-known intestinal pathogens in pigs. B. hyodysenteriae is the causative agent of swine dysentery, a disease with an important impact on pig production while B.
Vanessa Casas +4 more
doaj +6 more sources
Potential for Zoonotic Transmission of Brachyspira pilosicoli [PDF]
To the Editor: Anaerobic intestinal spirochetes of the genus Brachyspira colonize the large intestine (1). Most Brachyspira species have a restricted host range, whereas Brachyspira (formerly Serpulina) pilosicoli colonizes a variety of animal and bird species and humans. B. pilosicoli is an important colonic pathogen of pigs and chickens (2).
David J. Hampson +2 more
doaj +4 more sources
A survey on the occurrence of Brachyspira pilosicoli and Brachyspira hyodysenteriae in growing-finishing pigs [version 2; peer review: 2 approved, 1 approved with reservations] [PDF]
Background: The major pathogenic intestinal spirochetes affecting pigs during the growing- finishing stage of production include Brachyspira hyodysenteriae and Brachyspira pilosicoli.
Arkadiusz Dors +2 more
doaj +5 more sources
A novel TaqMan 5‐plex real‐time PCR using a combination of locked nucleic acid‐modified (LNA)‐ and minor groove binding (MGB)‐conjugated DNA probes was developed for identification and differentiation between the four main pathogenic Brachyspira species ...
Simone Scherrer, Roger Stephan
doaj +2 more sources
Assessment of animal diseases caused by bacteria resistant to antimicrobials: Swine
In this opinion, the antimicrobial‐resistant bacteria responsible for transmissible diseases that constitute a threat to the health of pigs have been assessed. The assessment has been performed following a methodology based on information collected by an
EFSA Panel on Animal Health and Welfare (AHAW) +26 more
doaj +2 more sources
Identification of small molecule inhibitors for the Brachyspira pilosicoli glutamate racemase (Bp-MurI) enzyme using a computational and experimental approach [PDF]
Brachyspira pilosicoli (Bp) causes intestinal spirochaetosis in poultry and pigs and more rarely in humans. In this pilot study, we used a computational approach to identify potential small molecule inhibitors for the Bp glutamate racemase (Bp-MurI), an ...
Ravi Kant +2 more
doaj +2 more sources
The intestinal spirochete Brachyspira pilosicoli attaches to cultured Caco-2 cells and induces pathological changes. [PDF]
BACKGROUND:Brachyspira pilosicoli is an anaerobic spirochete that has received relatively little study, partly due to its specialized culture requirements and slow growth. This bacterium colonizes the large intestine of various species, including humans;
Ram Naresh, Yong Song, David J Hampson
doaj +2 more sources
Evidence of homologous recombination as a driver of diversity in Brachyspira pilosicoli. [PDF]
The enteric, pathogenic spirochaete Brachyspira pilosicoli colonizes and infects a variety of birds and mammals, including humans. However, there is a paucity of genomic data available for this organism.
Pandey A +7 more
europepmc +6 more sources
Brachyspira pilosicoli-induced avian intestinal spirochaetosis. [PDF]
Avian intestinal spirochaetosis (AIS) is a common disease occurring in poultry that can be caused by Brachyspira pilosicoli, a Gram-negative bacterium of the order Spirochaetes. During AIS, this opportunistic pathogen colonises the lower gastrointestinal (GI) tract of poultry (principally, the ileum, caeca, and colon), which can cause symptoms such as ...
Le Roy CI +4 more
europepmc +7 more sources
Human Intestinal Spirochetosis Shows Higher Positivity in Sessile Serrated Lesions Than in Tubular Adenomas With Preferential Colonization of Absorptive Epithelium. [PDF]
Human intestinal spirochetosis (HIS) positivity was significantly higher in sessile serrated lesions (SSLs) than in tubular adenomas (TAs). HIS preferentially colonized absorptive epithelium, which is abundant in SSLs but limited in TAs, indicating that differences in absorptive epithelial abundance account for the higher HIS positivity in SSLs ...
Matoba H +6 more
europepmc +2 more sources

