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The role of bracken fern illudanes in bracken fern-induced toxicities
Mutation Research/Reviews in Mutation Research, 2019Bracken fern is carcinogenic when fed to domestic and laboratory animals inducing bladder and ileal tumours and is currently classified as a possible human carcinogen by IARC. The carcinogenic illudane, ptaquiloside (PTQ) was isolated from bracken fern and is widely assumed to be the major bracken carcinogen. However, several other structurally similar
P.J. O’Connor +3 more
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Separation of carcinogenic fraction of bracken fern
Cancer Letters, 1984Isolation of the carcinogen in the boiling water extract of bracken fern was conducted by following the active principle with a carcinogenicity bioassay. Fractionation of the bracken extract was carried out using adsorption on resin (Amberlite XAD-2 and TOYOPEARL HW-40 (c] and organic solvent extraction.
Iwao Hirono +10 more
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Passage of Bracken Fern Toxicity into Milk
Nature, 1972BRACKEN (Pteridium aquilinum) and extracts of the plant have pluripotent carcinogenic and mutagenic properties, and if administered in sufficient concentration are acutely toxic to species as varied as mice and bovines1–9. The causative factor(s) of these different biological activities seem to be identical; they are produced by the same purified ...
I A, Evans +2 more
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Mechanism of bracken fern carcinogenesis
2022The ubiquitous bracken fern (genus Pteridium) is the only higher plant known to cause cancer naturally in animals. In addition to the well-recognised syndromes of thiamine deficiency, acute haemorrhage associated with myeloid aplasia and blindness due to retinal degeneration, it causes neoplasia of the urinary bladder and in some circumstances, of the ...
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THE INDUCTION OF APOGAMY IN THE BRACKEN FERN
Canadian Journal of Botany, 1960A new method of inducing apogamy in normal fern gametophytes of Pteridium aquilinum has been demonstrated. Entire plants, apparently isolated sporophytic members, and structures of an intermediate nature between sporophyte and gametophyte were produced.
Dean P. Whittier, Taylor A. Steeves
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New Zealand Veterinary Journal, 1952
Abstract Extract Poisoning of cattle by bracken fern (Pteridium aquilinum) has long been a serious problem on some of the poorer land where eradication of bracken is difficult or uneconomic. The problem occurs also on some better-class land since not infrequently cattle are used to crush out the bracken in the first stages of development of the land or
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Abstract Extract Poisoning of cattle by bracken fern (Pteridium aquilinum) has long been a serious problem on some of the poorer land where eradication of bracken is difficult or uneconomic. The problem occurs also on some better-class land since not infrequently cattle are used to crush out the bracken in the first stages of development of the land or
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Carcinogenic Principles Isolated from Bracken Fern
CRC Critical Reviews in Toxicology, 1986The carcinogenicity of bracken fern, Pteridium aquilinum, was demonstrated most clearly by the experiment of Evans and Mason in 1965. We have performed fractionation of the aqueous extract by means of the assay based on carcinogenicity and isolated an unstable norsesquiterpene glucoside of illudane type named ptaquiloside (PT). It was proved that PT is
Iwao Hirono, Elizabeth K. Weisburger
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Human Carcinogenesis and Bracken Fern: A Review of the Evidence
Current Medicinal Chemistry, 2002The complex taxon embraced in the Pteridium genus, popularly known as bracken fern and notorious weeds in many parts of the world, is one of the few vascular plants known to induce cancer naturally in animals. It has been known for long to be acutely toxic to livestock and sublethal chronic oral feeding of bracken fronds leads to cancerous lesions in ...
M E, Alonso-Amelot, M, Avendaño
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Effect of storage on carcinogenic activity of bracken fern
Cancer Letters, 1981Effect of storage on carcinogenic activity of bracken fern was examined with inbred strain ACI rats of both sexes. The experiment was broken down into 3 groupings: Group I received a diet containing fresh dry bracken powder: Group II received a diet which contained the same dry bracken powder used in Group I but preserved for 1 year at 4 degrees C ...
T, Kawai +4 more
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OBSERVATIONS ON THE CULTURE OF ROOTS OF THE BRACKEN FERN
Canadian Journal of Botany, 1963Roots of the bracken fern (Pteridium aquilium) isolated from a sexual sporeling have been successfully cultured in vitro. Initial studies were directed toward a definition of growth conditions and media. The roots are now cultured in a very simple medium consisting of a Knudson mineral salt solution with added minor elements and 1.5% sucrose, at an ...
Jane N. Partanen, Carl R. Partanen
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