Results 1 to 10 of about 1,131 (142)
Química Nova, 2005 The indan ring system is present in several compounds with important pharmacological properties. In this account recent examples of selected methods (Friedel-Crafts acylation, cycloaddition reactions, ring contraction, cyclization and resolution) for the
Helena M. C. Ferraz +3 more
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Friedel-Crafts chemistry. Part 55. Competing indan versus tetralin ring formations during Friedel-Crafts intramolecular cyclialkylations of some selected di-, tri- and tetraphenylated alkanols [PDF]
Assiut University Journal of Multidisciplinary Scientific Research, 2018 Friedel-Crafts cyclialkylations of six phenylated alkanols 2a-f to new substituted indans andtetralins mediated by AlCl3/CH3NO2, 85% H2SO4 and/or PPA are described.
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Plant-Mediated Enantioselective Transformation of Indan-1-One and Indan-1-ol [PDF]
Catalysts, 2019 The main purpose of this work was to discover the way to obtain pure enantiomers of indan-1-ol. The subject of the study was the ability of the plant enzyme system to reduce the carbonyl group of indan-1-one, as well as to oxidize the hydroxyl group of racemic indan-1-ol.
Wanda Mączka +3 more
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Nouveaux corps odorants dans Ie domaine des muscs polycycliques
CHIMIA, 1992 Polyalkyl-tetralins and -indans are well known as starting materials for polycyclic musks obtained by Friedel-Crafts acylation. If, instead, such hydrocarbons are subjected to benzylic (electrochemical) oxidation, new musks are obtained.
Josiane Baudin +2 more
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1′-Methyl-4′-phenyldispiro[indan-2,2′-pyrrolidine-3′,2′′-indan]-1,3,1′′-trione [PDF]
Acta Crystallographica Section E Structure Reports Online, 2011 The conformation of the title compound, C(27)H(21)NO(3), is stabilized by a weak intra-molecular C-H⋯O hydrogen bond, which generates an S(6) ring motif. The pyrrolidine ring adopts a half-chair conformation. Both of the other five-membered rings are in envelope conformations. No significant inter-molecular hydrogen bonds are observed.
Ang Chee Wei +4 more
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Journal of the Brazilian Chemical Society, 2001 The reaction of a series of 1-tetralones with thallium trinitrate supported on Montmorillonite K-10 clay led to products of ring contraction (methyl indan-1-carboxylates) and/or alpha-oxidation (2-methoxy-1-tetralones), in variable yields.
Ferraz Helena M. C. +3 more
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Journal of the Brazilian Chemical Society, 2006 The rearrangement of beta,gamma-unsaturated esters, such as 2-(3,4-dihydronaphthalen-1-yl)-propionic acid ethyl ester, with thallium trinitrate (TTN) in acetic acid leads to 3-indan-1-yl-2-methyl-3-oxo-propionic acid ethyl ester in good yield, through a ...
Silva Jr. Luiz F. +2 more
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Research progress of donepezil for treating mild to moderate Alzheimer's disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2017 Donepezil is the second generation of cholinesterase inhibitors (ChEIs), which has a good effect on mild to moderate Alzheimer's disease (AD). In recent years, there were a lot of studies on the mechanism of donepezil. This paper mainly introduces the
Xin-xin LI, Yun-yun ZHANG, Bin WANG
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Plant-Mediated Enantioselective Transformation of Indan-1-one and Indan-1-ol. Part 2 [PDF]
Molecules, 2019 The main purpose of this publication was to obtain the S-enantiomer of indan-1-ol with high enantiomeric excess and satisfactory yield. In our research, we used carrot callus cultures (Daucus carota L.), whereby the enzymatic system reduced indan-1-one and oxidized indan-1-ol.
Wanda Mączka +3 more
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Bioorganic ChemistryThe indane scaffold, prevalent in bioactive natural products, underpins numerous therapeutics. Our group developed a series of 1,2-indane dimers, including PH46A (9), for inflammatory and autoimmune diseases. This study details the design, synthesis and characterisation of 21 compounds, including 2,2-disubstituted indanones (16a-16h), indanols (17a-17h)
Tao, Zhang +9 more
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