Results 41 to 50 of about 94,989 (252)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Herbal and Alcohol-Free Mouthwashes as Chlorhexidine Alternatives for Preventing Enamel Demineralization in Orthodontic Patients: An In Vitro Study

open access: yesDentistry Journal
Background/Objectives: Chlorhexidine (CHX) and alcoholic (A+) mouthwashes are associated with adverse oral effects. Therefore, this study compared the efficacies of non-alcoholic mouthwashes, including fluoride (A−) and herbal (Hr) rinses, for preventing
Nyema A. Abualsaud   +9 more
doaj   +1 more source

Topological optimization of opening fence brackets on ring-stiffened cylindrical shell

open access: yesZhongguo Jianchuan Yanjiu, 2018
[Objectives] Stress concentration is prone to take place at connections between the opening fence and ring ribs of a ring-stiffened cylindrical shell under external pressure.
SONG Xiaofei   +4 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

REGARDING THE QUALITY OF THE VEHICLE BACKSEAT FRAME ARMATURE RS 60% [PDF]

open access: yesFiabilitate şi Durabilitate, 2018
This paperwork identifies the unconformity from the backseat frame armature RS60% welding of a vehicle, respective the seatbelt bracket position. Causes and fixing that the seatbelt bracket not to be able to rotate around its axis.
Monica BÂLDEA   +2 more
doaj  

Effect of Orthodontic Bracket Base Structure on Shear Bond Strength

open access: yes, 2006
Direct bonding is the method of choice for attaching fixed orthodontic appliances. These fixed appliances are produced with various bonding bases. The present study aims to compare shear bond strengths (SBS) and fracture characteristics of the bracket ...
Sıddık Malkoç   +3 more
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

Friktionsverhalten von neuentwickelten Kunststoffkappenvarianten für das RED-Bracket [PDF]

open access: yes, 2020
Die vorliegende experimentelle in vitro Forschungsarbeit befasst sich mit Untersuchung von neu entwickelten, funktionellen Kappen für ein neuartiges Bracket-System.
Gruber, Philip
core   +1 more source

Evaluation of the Effects of Different Mouthrinses on the Color Stability of One Type of Glass Ionomer, Compomer and Giomer [PDF]

open access: yesJournal of Dental Materials and Techniques, 2015
Objectives: The aim of this study was to evaluate the effect of four commercially available mouthrinses on the color stability of one type of glass ionomer, giomer and compomer. Method: 60 disc-shaped specimens, 180 in total (7*2mm), fabricated from each
Shaghayegh Razavi   +3 more
doaj  

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