Results 121 to 130 of about 94,466 (297)

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

Atrial Fibrillation-Related Bradycardia and/or Bradycardia-Related Atrial Fibrillation: When and How to Intervene

Introduction/Objective: Atrial fibrillation (AF) could present with slow ventricular-response; bradycardia could facilitate the emergence of AF. The conviction that one “does not succumb” from bradycardia as an escape rhythm will emerge unless one ...
Manolis, Antonis S., Manolis, Antonis A., Manolis, Theodora A.   +2 more
core  

Antimicrobial Residues in a Key Cerrado River: Distribution, Persistence, and Effects on Zebrafish Embryo‐Larval Development

Environmental Toxicology, EarlyView.
ABSTRACT The current study aimed to quantify the antimicrobials amoxicillin (AMX), cefazolin (CFZ), chloramphenicol (CHL), metronidazole (MTZ), and sulfamethoxazole (SX) in effluents and surface water of an important Cerrado river, calculate their half‐lives, and analyze their ecotoxicity following single and combined exposures.
Náthala Maria Simão, Igor Romeiro dos Santos, Jerônimo Raimundo de Oliveira Neto, Flávio Olimpio Sanches Neto, Felipe Cirqueira Dias, Jéssyca Moreira Morais, Lorranny Pereira de Assis Valadares, Naiara Raica Lopes de Oliveira, Mirelle Garcia Silva Bailão, Luiz Carlos da Cunha, Valter Henrique Carvalho‐Silva, Thiago Lopes Rocha, Elisa Flávia Luiz Cardoso Bailão   +12 more
wiley   +1 more source

A Prospective Clinical Study to Assess the Efficiency of Subarachnoid Block as Sole Anesthetic Method in Neonates Undergoing Infraumbilical Surgeries

Journal of Pharmacy and Bioallied Sciences
Background: Spinal anesthesia is increasingly used in neonates to minimize respiratory complications such as apnea and bradycardia. It also avoids delayed recovery associated with general anesthesia (GA) and provides stable intraoperative conditions for ...
Kaushal Kabir, Kovvuri Jhansi, Aseem Sharma, Akshay R. Nair, Manish Banjare   +4 more
doaj   +1 more source

Dihydroergotoxine-induced Bradycardia in Rats

, 1988
Dihydroergotoxine (0.01–0.3 mg kg−1 i.v.) decreased heart rate in pentobarbitone-anaesthetized rats. The bradycardia was reduced but not blocked by pre-treatment with guanethidine, yohimbine, propranolol or pithing.
Jacques Roquebert, Bruno Grenié
core   +1 more source

Evaluating Thiram‐Induced Embryotoxicity Using Integrated In Silico, In Vitro, and Transcriptomic Approaches

Environmental Toxicology, EarlyView.
ABSTRACT Long‐term exposure to low‐dose food contact materials (FCMs) has raised concerns regarding developmental toxicity. In the present study, we prioritized FCMs with potential developmental toxicity using a weight‐of‐evidence computational model, which predicted 127 chemicals to be of high concern.
Chia‐Chi Ho, Chun‐Wei Tung, B. Linju Yen, Chen‐Yi Weng, Ju‐Hsin Hsu, Ming‐Hsien Tsai, Salim Arrokhman, Pinpin Lin   +7 more
wiley   +1 more source

Bradyarrhythmias secondary to topical levobunolol hydrochloride solution

Clinical Interventions in Aging, 2014
Lianjun Lin,* Yuchuan Wang,* Yan Chen, Meilin Liu Geriatric Department, Peking University First Hospital, Beijing, People’s Republic of China *These authors contributed equally to this work Abstract: An 88-year-old man was admitted with fatigue,
Lin LJ, Wang YC, Chen Y, Liu ML
doaj  

Hypothyroidism and sinus dysfunction associated with lithium-paliperidone combination therapy for bipolar disorder with psychotic symptoms: a case report

Frontiers in Psychiatry
Background and aimLithium is considered to be the first-line treatment for bipolar disorder, and paliperidone was approved for the treatment of schizophrenia and acute bipolar manic/mixed episodes.
Wenjian Wei, Yonglan Yang, Haifeng Wang, Yunbin Yang, Jizhou Liu, Jizhou Liu, Jinfeng Li   +6 more
doaj   +1 more source

Diazepam facilitates reflex bradycardia in conscious rats

, 1987
The effects of diazepam on cardiovascular function were assessed in conscious rats. Intravenous administration of diazepam (1-30 mg kg−1) produced a dose-dependent decrease in both the mean arterial pressure and the heart rate.
H J Liu, C P Yang, M T Lin, L S Chou
core   +1 more source

Presence of Nationally Banned Carbamates and Organophosphate Pesticides in Wild Carnivores, Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT As top predators, terrestrial carnivores face great risk of pesticide exposure and serve as sentinels of environmental contamination. Additionally, terrestrial carnivores are frequently threatened by intentional or secondary poisoning with highly toxic compounds, such as carbamates and organophosphates.
Marina Pellegrino da Silva, Vagner Gonçalves‐Junior, Mauricio Candido da Silva, André Rinaldi Fukushima, Rose Lilian Gasparini‐Morato, Helenice de Souza Spinosa, Ana Carolina Ewbank, Carlos Sacristán, Ana de la Torre, José Luiz Catão‐Dias, Pedro Enrique Navas‐Suárez   +10 more
wiley   +1 more source