Results 101 to 110 of about 83,150 (251)

Longitudinal Doppler assessment and perinatal outcomes in early‐set intrauterine growth restriction fetuses

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In early‐onset fetal growth restriction requiring delivery before 30 weeks, shorter intervals to abnormal ductus venosus and umbilical artery Doppler findings are associated with severe morbidity and mortality, highlighting the prognostic value of longitudinal Doppler assessment.
Edurne Mazarico   +10 more
wiley   +1 more source

Impact of oxytocin discontinuation on fetal heart rate and uterine contractility: A pre‐specified ancillary analysis embedded within a randomized trial

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
The impact of oxytocin discontinuation at the onset of the active phase of labor on fetal heart rate (FHR) patterns and uterine activity; One hour following discontinuation, the mean FHR baseline slightly increased, FHR patterns improved—particularly with reduced decelerations and improved variability—and uterine activity decreased. Moreover, among the
Lise Lafforgue   +7 more
wiley   +1 more source

Prognostic models for predicting sight‐threatening retinopathy of prematurity in preterm infants: A systematic review

open access: yesActa Ophthalmologica, EarlyView.
Abstract To identify, describe and critically appraise studies developing and/or validating models for predicting sight‐threatening retinopathy of prematurity (ROP) in preterm infants undergoing screening in neonatal intensive care units. PubMed, Embase via Ovid, trial registers, and grey literature were searched from inception to 21 October 2025 ...
Stella Moutzouri   +7 more
wiley   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia   +6 more
wiley   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam   +3 more
wiley   +1 more source

Symptomatic Bradycardia and Syncope due to Ophthalmic Timolol Maleate

open access: yesÇukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Timolol maleate is a non-selective (effective to and szlig;1 and and szlig;2 receptors) is a topical beta blocker drug which is used in the treatment of glaucoma. Besides its topical impact, it may have some systemic side effects.
Muge Gulen   +4 more
doaj  

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang   +4 more
wiley   +1 more source

Response to equine cardiac adverse events during sports

open access: yesEquine Veterinary Education, EarlyView.
Summary Cardiac adverse events and sudden death are a feared scenario for equine veterinarians, with serious consequences for animal health, riders' safety and the social licence to operate equestrian sports. The response to equine cardiac adverse events (CAEs) during sports is poorly defined.
C. Navas de Solis   +9 more
wiley   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

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