Results 91 to 100 of about 180,641 (332)

Cardiovascular Complications Resulting from Topical Lidocaine Application

International Journal of Gerontology, 2008
Topical lidocaine is one of the most commonly used anesthetics in the emergency department (ED). The advantages of topical anesthesia include ease of application, minimal discomfort on administration, and rapid onset of anesthesia. Systemic toxic effects
Feng Lin, Wen-Han Chang, Yu-Jang Su, Cheng-Ho Tsai   +3 more
doaj   +1 more source

Tachycardia-bradycardia syndrome: Electrophysiological mechanisms and future therapeutic approaches (Review)

International Journal of Molecular Medicine, 2017
Sick sinus syndrome (SSS) encompasses a group of disorders whereby the heart is unable to perform its pacemaker function, due to genetic and acquired causes.
G. Tse, Tong Liu, K. H. C. Li, V. Laxton, A. O. Wong, Y. W. Chan, Wendy Keung, C. Chan, Ronald A. Li   +8 more
semanticscholar   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

ESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo, Si Shi, Yutong Guo, Jie Xiong, Bo Wang, Zengxiang Dong, Dianyu Gao, Yingfeng Tu   +7 more
wiley   +1 more source

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad, Jeanne du Fay de Lavallaz, Michael J. Zhang, Thanat Chaikijurajai, Bo Ye, Prabhjot S. Nijjar, Julie A. Lahiri, Cindy M. Martin, Tamas Alexy, Markus Meyer   +9 more
wiley   +1 more source

Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. [PDF]

, 2013
Organophosphorus pesticides (OPs) are implicated in human asthma. We previously demonstrated that, at concentrations that do not inhibit acetylcholinesterase activity, the OP parathion causes airway hyperreactivity in guinea pigs as a result of ...
Allison D. Fryer, Becky J. Proskocil, Borish L, Crain EF, Crinnion WJ, David B. Jacoby, Donald A. Bruun, Gallo MA, Grodzki AC, Lu C, Nico van Rooijen, Pamela J. Lein, Rozyk KJ   +12 more
core   +1 more source

Development and validation of a dual sensing scheme to improve accuracy of bradycardia and pause detection in an insertable cardiac monitor.

Heart Rhythm, 2017
BACKGROUND Undersensing of premature ventricular beats and low-amplitude R waves are primary causes for inappropriate bradycardia and pause detections in insertable cardiac monitors (ICMs).
R. Passman, J. Rogers, S. Sarkar, J. Reiland, Erin Reisfeld, J. Koehler, S. Mittal   +6 more
semanticscholar   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Requirement for sphingosine kinase 1 in mediating phase 1 of the hypotensive response to anandamide in the anaesthetised mouse [PDF]

, 2019
In the isolated rat carotid artery, the endocannabinoid anandamide induces endothelium-dependent relaxation via activation of the enzyme sphingosine kinase (SK).
Alganga, Husam, Ballantyne, Margaret D., Ewart, Marie-Ann, Fertig, Bracy, Greig, Fiona H., Kazi, Zeshan H., Kennedy, Simon, Nather, Katrin, Pyne, Nigel J., Pyne, Susan, Zaborska, Karolina E.   +10 more
core   +2 more sources

Ictal semiology in fronto‐opercular epilepsy: A systematic review

Epileptic Disorders, EarlyView.
Abstract A systematic review of the ictal semiology of fronto‐opercular seizures in focal epilepsy was carried out to assess possible anatomical‐clinical correlations and help guide interpretation of ictal semiology during pre‐surgical evaluation. PubMed and Embase databases were searched using the following keywords: “fronto‐opercular OR frontal ...
Zeynep Gokce‐Samar, Alexandra Montavont, Marion Comajuan, Julitta de Bellescize, Eleni Panagiotakaki, Marietta Papadopoulou, Matthildi‐Athina Papathanasiou‐Terzi, Joseph Toulouse, Alexis Arzimanoglou, Karine Ostrowsky‐Coste   +9 more
wiley   +1 more source

Tracheal suctioning improves gas exchange but not hemodynamics in asphyxiated lambs with meconium aspiration. [PDF]

, 2015
BackgroundCurrent neonatal resuscitation guidelines recommend tracheal suctioning of nonvigorous neonates born through meconium-stained amniotic fluid.MethodsWe evaluated the effect of tracheal suctioning at birth in 29 lambs with asphyxia induced by ...
Gugino, Sylvia F, Koenigsknecht, Carmon, Lakshminrusimha, Satyan, Mathew, Bobby, Nair, Jayasree, Nielsen, Lori, Rawat, Munmun, Swartz, Daniel D   +7 more
core