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General Pharmacology: The Vascular System, 1997
1. The last decade has witnessed a phenomenal increase in our understanding of the pharmacology of bradykinin receptors, and has led to an appreciation of a key role for the peptide kinins as proinflammatory mediators. This short review summarises the major changes that have taken place in the expanding area of bradykinin receptor pharmacology, and ...
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1. The last decade has witnessed a phenomenal increase in our understanding of the pharmacology of bradykinin receptors, and has led to an appreciation of a key role for the peptide kinins as proinflammatory mediators. This short review summarises the major changes that have taken place in the expanding area of bradykinin receptor pharmacology, and ...
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Bradykinin receptor antagonists
Medicinal Research Reviews, 1990Bradykinin and its active metabolites are produced at the sites of their actions by kallikreins. They potently elicit a variety of biological effects: hypotension, bronchoconstriction, gut and uterine contraction, epithelial secretion in airway, gut, and exocrine glands, vascular permeability, pain, connective tissue proliferation, and eicosanoid ...
R M, Burch, S G, Farmer, L R, Steranka
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Journal of Cardiovascular Pharmacology, 1990
Because all antibodies to bradykinin described to date more or less cross-react with larger and smaller bradykinin derivatives, the aim of the present study was the induction of a specific antibody against bradykinin. A bradykinin derivative, containing a Cys residue at position 6 instead of Ser, was linked to BSA by using a new heterobifunctional ...
U, Hilgenfeldt, R, Linke, W, König
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Because all antibodies to bradykinin described to date more or less cross-react with larger and smaller bradykinin derivatives, the aim of the present study was the induction of a specific antibody against bradykinin. A bradykinin derivative, containing a Cys residue at position 6 instead of Ser, was linked to BSA by using a new heterobifunctional ...
U, Hilgenfeldt, R, Linke, W, König
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Radioimmunoassay of Bradykinin
Nature, 1967IN the past few years highly sensitive and specific radioimmunological methods have been developed for the determination of many polypeptide hormones1. Radioimmunoassays are usually based on the competitive reaction of a measured amount of polypeptide hormone labelled with iodine-125 and iodine-131 and varying amounts of unlabelled hormone with hormone
H, Rinderknecht +2 more
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Experientia, 1962
Incubates of the venom ofCrotalus atrox resp. Padutin-Bayer (Kallikrein) with globulines from ox plasma were bioassayed on theileum of guineapigs, theduodenum of rats and theblood-pressure of rabbits and compared with the effects of synthetic bradykinin.
P, HOLTZ, B, HEICKE, S, BARCK
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Incubates of the venom ofCrotalus atrox resp. Padutin-Bayer (Kallikrein) with globulines from ox plasma were bioassayed on theileum of guineapigs, theduodenum of rats and theblood-pressure of rabbits and compared with the effects of synthetic bradykinin.
P, HOLTZ, B, HEICKE, S, BARCK
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Bradykinin Potentiating Factor
Chest, 1971The bradykinin-potentiating factor (BPF) is a component of Bothrops jararaca venom which potentiates in vitro as well as in vivo some pharmacological effects of bradykinin (Ferreira, 1964; 1965). This communication deals with its purification, biochemical characteristics, pharmacological actions,and some considerations of the mechanism of bradykinin ...
L J, Greene, S H, Ferreira, J M, Stewart
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