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Cerebellar Pleomorphic Xanthoastrocytoma with BRAF V600E Mutation

World Neurosurgery, 2020
Pleomorphic xanthoastrocytoma (PXA) is a rare type of astrocytoma with a peak incidence from 10 to 19 years of age. PXA is found most commonly in the supratentorium. When it is present in atypical areas such as the infratentorium, it is often overlooked as a potential differential diagnosis.This report discusses the case of an 18-year-old woman with a ...
Sang Ho Kim   +4 more
openaire   +2 more sources

BRAF V600E Mutations in Endometrial Adenocarcinoma

Diagnostic Molecular Pathology, 2013
The BRAF V600E somatic mutation is recognized as an oncogenic driver of many human cancers involving the MAPK/ERK pathway. Colorectal and lung cancers associated with the BRAF V600E mutation often demonstrated mucinous morphology. This study hypothesized that the BRAF V600E mutation may be associated with mucinous morphology in endometrial cancer and ...
Mai, He   +5 more
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BRAF V600E mutation-specific antibody: A review

Seminars in Diagnostic Pathology, 2015
The significance of BRAF mutations in neoplasia was first recognized in 2002 when mutations were discovered in a broad range of cancers. Numerous subsequent studies expanded our understanding of BRAF V600E as a critical diagnostic, prognostic, and predictive biomarker in many cancers.
Lauren L, Ritterhouse   +1 more
openaire   +2 more sources

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