Results 171 to 180 of about 37,220 (200)

Prospective immunohistochemical analysis of BRAF V600E mutation in melanoma

Human Pathology, 2015
The v-raf murine sarcoma viral oncogene homolog B1 (BRAF) V600E mutation is the most common activating genetic alteration of this oncogene and a predictive marker for the therapeutic use of BRAF inhibitors in melanoma. Our aim was to evaluate the performance of BRAF V600E mutation-specific monoclonal antibody (VE1) in a prospective diagnostic setting ...
Thiel Alexandra, Ristimaki Ari, Orpana Arto, Hernberg Micaela, Moza Monica, Jahkola Tiina, Thiel Alexandra, Ristimaki Ari, Orpana Arto, Hernberg Micaela, Moza Monica, Jahkola Tiina   +11 more
openaire   +2 more sources

BRAF V600E mutational status in pediatric thyroid cancer

Pediatric Blood & Cancer, 2014
AbstractBackgroundClinical outcome of papillary thyroid carcinoma (PTC) in children differs significantly from that of adults. There is no clear explanation of this difference although previous studies have demonstrated a lower prevalence of the BRAFV600E mutation in PTC of children.
Lauren E, Henke, Stephanie M, Perkins, John D, Pfeifer, Changquing, Ma, Yumei, Chen, Todd, DeWees, Perry W, Grigsby   +6 more
openaire   +2 more sources

BRAF V600E mutation in neocortical posterior temporal epileptogenic gangliogliomas

Journal of Clinical Neuroscience, 2015
The aim of this study was to verify the presence of BRAF mutations in a series of six patients affected by drug-resistant focal epilepsy associated with neocortical posterior temporal gangliogliomas (GG) who were subjected to lesionectomy between June 2008 and November 2013.
Martinoni, M., Marucci, G., DE BIASE, DARIO, Rubboli, G., Volpi, L., Riguzzi, P., Marliani, F., Toni, F., Naldi, I., BISULLI, FRANCESCA, TINUPER, PAOLO, Michelucci, R., BARUZZI, AGOSTINO, TALLINI, GIOVANNI, Giulioni, M.   +14 more
openaire   +2 more sources

BRAF V600E mutation detection by immunohistochemistry in colorectal carcinoma

Genes, Chromosomes and Cancer, 2013
The serine/threonine‐protein kinase B‐raf (BRAF) is an oncogene mutated in various neoplasms, including 5–15% of colorectal carcinomas. The T1799A point mutation, responsible for a large majority of these alterations, results in an amino acid substitution (V600E) causing the constitutive activation of a protein kinase cascade.
Kajsa, Affolter, Wade, Samowitz, Sheryl, Tripp, Mary P, Bronner   +3 more
openaire   +2 more sources

BRAF(V600E) mutation and the biology of papillary thyroid cancer

Endocrine Related Cancer, 2008
BRAF((V600E)) mutation is the most frequent genetic alteration in papillary thyroid carcinomas (PTCs) that are 80-90% of all thyroid cancers. We evaluated the relationship between BRAF((V600E)) and tumor, host, and environmental factors in PTCs from all geographical areas of Sicily.
FRASCA, FRANCESCO, NUCERA C, PELLEGRITI G, GANGEMI P, ATTARD M, STELLA M, LODA M, VELLA V, GIORDANO C, TRIMARCHI F, MAZZON E, BELFIORE A, VIGNERI R., VELLA, VERONICA   +13 more
openaire   +7 more sources

BRAF V600E mutations in bile duct adenomas

Hepatology, 2014
Anaïs, Pujals, Giuliana, Amaddeo, Claire, Castain, Paulette, Bioulac-Sage, Philippe, Compagnon, Jessica, Zucman-Rossi, Daniel, Azoulay, Karen, Leroy, Elie Serge, Zafrani, Julien, Calderaro   +9 more
openaire   +2 more sources

Vemurafenib in Melanoma with BRAF V600E Mutation

New England Journal of Medicine, 2011
Dalle, Stéphane, Poulalhon, Nicolas, Thomas, Luc   +2 more
openaire   +4 more sources

Clinicopathologic Correlations of BRAF V600E Mutation and Braf V600E Immunohistochemistry in Ameloblastomas

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2015
J. CHANG, Y.P. WANG, C.P. CHIANG
openaire   +1 more source

V600E BRAF versus Non-V600E BRAF Mutated Lung Adenocarcinomas: Cytomorphology, Histology, Coexistence of Other Driver Mutations and Patient Characteristics.

Acta cytologica, 2018
We analyzed the morphologic features and clinical characteristics of lung adenocarcinomas (ACAs) harboring mutated BRAF.A review of the histology/cytology of BRAF-mutated lung ACAs was performed at the Johns Hopkins Hospital from January 1, 2013, to January 1, 2015.
Kevan J, Salimian, Roghayeh, Fazeli, Gang, Zheng, David, Ettinger, Zahra, Maleki   +4 more
openaire   +1 more source

Frequent BRAF V600E Mutations in Metanephric Stromal Tumor

American Journal of Surgical Pathology, 2016
Pedram, Argani, Justin, Lee, George J, Netto, Gang, Zheng, Ming, Tseh-Lin, Ben Ho, Park   +5 more
openaire   +2 more sources