Results 251 to 260 of about 236,444 (370)

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Independence of Peripheral Brain-Derived Neurotrophic Factor from Depression and Anxiety Symptoms in Cocaine Use Disorder: An Initial Description. [PDF]

open access: yesInt J Mol Sci
Islas-Preciado DM   +8 more
europepmc   +1 more source

A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor.

open access: yesJournal of Psychiatric Research, 2015
Kristin L. Szuhany   +2 more
semanticscholar   +1 more source

A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease

open access: bronze, 2000
Hiroshi Kunugi   +8 more
openalex   +1 more source

Brain-derived Neurotrophic Factor Enhances Neuronal Translation by Activating Multiple Initiation Processes [PDF]

open access: hybrid, 2001
Nobuyuki Takei   +4 more
openalex   +1 more source

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

open access: yesIbrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou   +6 more
wiley   +1 more source

Epigenetic regulation in cognitive impairment: Focus on N6‐methyladenosine modification and its potential role in perioperative neurocognitive disorders

open access: yesIbrain, EarlyView.
N6‐methyladenosine (m6A), a key mammalian mRNA modification, affects cognition via gene regulation. This review explores its role in cognition and perioperative neurocognitive disorders (PNDs). Animal studies link m6A dysregulation to PND‐related mechanisms, but direct evidence is preliminary.
Ting Liu   +10 more
wiley   +1 more source

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