Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Independence of Peripheral Brain-Derived Neurotrophic Factor from Depression and Anxiety Symptoms in Cocaine Use Disorder: An Initial Description. [PDF]
Islas-Preciado DM+8 more
europepmc +1 more source
A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor.
Kristin L. Szuhany+2 more
semanticscholar +1 more source
Brain-derived Neurotrophic Factor Enhances Neuronal Translation by Activating Multiple Initiation Processes [PDF]
Nobuyuki Takei+4 more
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This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou+6 more
wiley +1 more source
Socioeconomic factors, brain-derived neurotrophic factor Val66Met polymorphism, and cortical structure in children and adolescents. [PDF]
Merz EC+7 more
europepmc +1 more source
N6‐methyladenosine (m6A), a key mammalian mRNA modification, affects cognition via gene regulation. This review explores its role in cognition and perioperative neurocognitive disorders (PNDs). Animal studies link m6A dysregulation to PND‐related mechanisms, but direct evidence is preliminary.
Ting Liu+10 more
wiley +1 more source
Estimation of the Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) and Interleukin-1β and Their Correlation With Clinical Severity in Depression Patients: A Case-Control Study. [PDF]
Huded CB+7 more
europepmc +1 more source
Calcium regulation of the brain-derived neurotrophic factor gene
Steven Finkbeiner
openalex +2 more sources