Results 251 to 260 of about 183,340 (290)

Independence of Peripheral Brain-Derived Neurotrophic Factor from Depression and Anxiety Symptoms in Cocaine Use Disorder: An Initial Description. [PDF]

Int J Mol Sci
Islas-Preciado DM, Alcalá-Lozano R, Aguilar-Velazquez EP, Flores-Medina YG, Vega-Rivera NM, Estrada-Camarena E, Carino-Escobar R, González-Olvera JJ, Morelos-Santana ED.   +8 more
europepmc   +1 more source

P2X7 receptor antagonism suppresses epileptiform‐like activity in an inflammation‐primed human iPSC‐derived neuron model of drug‐resistant epilepsy

British Journal of Pharmacology, EarlyView.
Background and Purpose Neuroinflammation is increasingly recognised to contribute to drug‐resistant epilepsy. Activation of ATP‐gated P2X7 receptors has emerged as an important upstream mechanism, and increased P2X7 receptor expression is present in the seizure focus in rodent models and patients. Pharmacological antagonists of P2X7 receptors attenuate
Jaideep Kesavan, Yitao Wang, Klaus Dinkel, Michael Hamacher, Jochen H. M. Prehn, David C. Henshall, Tobias Engel   +6 more
wiley   +1 more source

Socioeconomic factors, brain-derived neurotrophic factor Val66Met polymorphism, and cortical structure in children and adolescents. [PDF]

Sci Rep
Merz EC, Morys F, Hansen M, Strack J, Jacobs L, Vainik U, Shishikura M, Myers B.   +7 more
europepmc   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Acute high-intensity interval training, but not reduced-exertion high-intensity interval training increase brain-derived neurotrophic factor in a block randomized controlled trial. [PDF]

Sci Rep
Evelis K, Kolesovs A, Rostoka E, Plakane L.   +3 more
europepmc   +1 more source

Reduced Levels of Brain Derived Neurotrophic Factor (BDNF) in the Serum of Diabetic Retinopathy Patients and in the Retina of Diabetic Rats

, 2012
Mohammad Shamsul Ola, Mohd Imtiaz Nawaz, Ahmed Abu El-Asrar   +2 more
openalex   +2 more sources

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

When genetics prevail: brain stimulation fails to overcome learning deficits from brain-derived neurotrophic factor <i>Val66Met</i>. [PDF]

Clin Neurophysiol Pract
Ramasawmy P, Iszak K, Brüshaber S, Kállay V, Ambrus GG, Paulus W, Antal A.   +6 more
europepmc   +1 more source

Review of Retinopathy of Prematurity Management in the Anti‐VEGF Era: Evolving Global Paradigms, Persistent Challenges and Our AI‐Assisted Future

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Retinopathy of prematurity (ROP) remains a major cause of preventable blindness in premature infants worldwide, with increasing incidence due to advancements in neonatal care. Management of ROP has been revolutionised by anti‐vascular endothelial growth factor (anti‐VEGF) treatments.
Kyle V. Marra, Jimmy S. Chen, Eric Nudleman, Shira L. Robbins   +3 more
wiley   +1 more source

Dual trajectories of serum brain-derived neurotrophic factor and cognitive function in people living with HIV. [PDF]

Sci Rep
Michael HU, Rapulana AM, Smit T, Xulu N, Danaviah S, Ramlall S, Oosthuizen F.   +6 more
europepmc   +1 more source