Results 251 to 260 of about 180,353 (291)

A comparison of commercial assays quantifying mature brain-derived neurotrophic factor (mBDNF) and its precursor (pro-BDNF) in human serum. [PDF]

open access: yesSci Rep
Olivas-Martínez A   +8 more
europepmc   +1 more source

Brain-Derived Neurotrophic Factor

2014
Brain-derived neurotrophic factor (BDNF), is a member of neurotrophin family having roles in survival, growth and function of neurons in the central and peripheral nervous system. BDNF mRNA and protein levels have been identified in the cerebellum, hippocampus, bulbus olfactorius, spinal cord, thalamus, prefrontal cerebral cortex, hypothalamus ...
David S. Middlemas, David B. Bylund
openaire   +3 more sources

Brain-Derived Neurotrophic Factor in Neonatal Seizures

Pediatric Neurology, 2021
Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, has an extensively studied classical role in neuronal growth, differentiation, survival, and plasticity. Neurotrophic, from the Greek neuro and trophos, roughly translates as "vital nutrition for the brain." During development, BDNF and its associated receptor tyrosine ...
Brennan J. Sullivan, Shilpa D. Kadam
openaire   +2 more sources

Brain-derived neurotrophic factor.

Growth factors (Chur, Switzerland), 2005
Since the purification of BDNF in 1982, a great deal of evidence has mounted for its central roles in brain development, physiology, and pathology. Aside from its importance in neural development and cell survival, BDNF appears essential to molecular mechanisms of synaptic plasticity.
Devin K, Binder, Helen E, Scharfman
openaire   +1 more source

Brain-derived neurotrophic factor in multiple sclerosis

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2019
The review presents data on brain-derived neurotrophic factor (BDNF), its structure and functions, the effect on the pathogenesis of experimental autoimmune encephalomyelitis and multiple sclerosis (MS). The correlation of BDNF level with clinical manifestations of MS and the changes of its level during disease-modifying therapy is considered.
A A, Semkina   +4 more
openaire   +2 more sources

The physiopathology of brain-derived neurotrophic factor

Physiological Reviews
BDNF is synthesized and secreted by excitatory neurons. Decades of work with animal models prepared the ground for interpreting the results of human genome analyses associating polymorphisms with memory deficits, mood disorders and dysregulation of food intake.
openaire   +2 more sources

Brain-derived neurotrophic factor in human platelets

Biochemical Pharmacology, 1997
A sensitive, capture enzyme-linked immunosorbent assay (CELISA) has been applied to the accurate and reproducible measurement of brain-derived neurotrophic factor (BDNF) protein in normal human blood platelets, a mean concentration of 1.03 +/- 0.04 ng (SEM)/mg of platelet protein being observed.
F B, Pliego-Rivero   +6 more
openaire   +2 more sources

The effect of brain-derived neurotrophic factor on angiogenesis

Journal of Huazhong University of Science and Technology [Medical Sciences], 2009
To investigate the in vitro and in vivo proangiogenic effects of brain-derived neurotrophic factor (BDNF), human umbilical vein endothelial cells (HUVECs) were isolated and cultured in primary culture. The effect of BDNF on the proliferation of HUVECs was examined by MTT assay.
Chunyan, Sun   +4 more
openaire   +2 more sources

Brain-derived neurotrophic factor in neurodegenerative diseases

Nature Reviews Neurology, 2009
Changes in the levels and activities of neurotrophic factors, such as brain-derived neurotrophic factor (BDNF), have been described in a number of neurodegenerative disorders, including Huntington disease, Alzheimer disease and Parkinson disease. It is only in Huntington disease, however, that gain-of-function and loss-of-function experiments have ...
C. Zuccato, E. Cattaneo
openaire   +2 more sources

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