Transcriptional regulation of human NMNAT2: insights from 3D genome sequencing and bioinformatics
The FEBS Journal, EarlyView.NMNAT2 is a valuable drug target, as low levels increase the risk of neurodegeneration. We employed 4C‐seq to identify NMNAT2 regulatory regions in the human genome, revealing distinct interactomes of the NMNAT2 promoter in undifferentiated and neuron‐like SH‐SY5Y cells. Additionally, we uncovered NMNAT2‐associated genes and transcription factors. This
Yu Chen Chang +5 more
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Acute high-intensity interval training, but not reduced-exertion high-intensity interval training increase brain-derived neurotrophic factor in a block randomized controlled trial. [PDF]
Sci RepEvelis K +3 more
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Brain-Derived Neurotrophic Factor (BDNF) in Huntington's Disease: Neurobiology and Therapeutic Potential. [PDF]
Curr NeuropharmacolAzman KF, Zakaria R.
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Genetic Association Study of Brain-Derived Neurotrophic Factor (BDNF) and Serotonin-Related Gene Variants in Suicide Attempters with Major Depressive Disorder and Control Persons. [PDF]
Genes (Basel)Kim T +11 more
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Estimation of the Serum Levels of Brain-Derived Neurotrophic Factor (BDNF) and Interleukin-1β and Their Correlation With Clinical Severity in Depression Patients: A Case-Control Study. [PDF]
CureusHuded CB +7 more
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