Results 291 to 300 of about 231,813 (388)

Assessing Causality Between Plasma Brain-Derived Neurotrophic Factor With Major Depression Disorder: A Bidirectional Mendelian Randomization Study. [PDF]

Brain Behav
Chen M, Huang HZ, Liu YH, Li Q, Fu LY, Hou CL.   +5 more
europepmc   +1 more source

Aerobic Exercise Restores Hippocampal Neurogenesis and Cognitive Function by Decreasing Microglia Inflammasome Formation Through Irisin/NLRP3 Pathway

Aging Cell, EarlyView.
Exercise improved PD pathology and memory by reducing microglial inflammation, apoptosis, and the formation of the NLRP3 inflammasome via irisin signaling. Irisin administration partially replicated the beneficial effects of exercise on PD pathology.
Renqing Zhao, Xin Tian, Haocheng Xu, Yuanxin Wang, Junjie Lin, Bin Wang   +5 more
wiley   +1 more source

Effect of Intracochlear Brain-Derived Neurotrophic Factor on Guinea Pig Sensorineural Hearing Loss. [PDF]

J Otolaryngol Head Neck Surg
Gigliotti D, Blakley B.
europepmc   +1 more source

Aged Gut Microbiota Contributes to Cognitive Impairment and Hippocampal Synapse Loss in Mice

Aging Cell, EarlyView.
Li et al. revealed that aged gut microbiota induces cognitive decline and microglia‐mediated synapse loss. Fecal Bifidobacterium pseudolongum abundance was reduced in patients with cognitive impairment and microbiota transplantation from patients with fewer B.p abundance yielded worse cognitive behavior in mice.
Mingxiao Li, Jiaoqi Ren, Yiyang Bao, Wenjing Wei, Xuefei Yu, Xiaofang He, Mutalifu gulisima, Lili Sheng, Ningning Zheng, Jianbo Wan, Houguang Zhou, Ling Zhao, Houkai Li   +12 more
wiley   +1 more source

Association of Brain-derived Neurotrophic Factor Polymorphisms With Alcohol Use Disorder: An Updated Meta-Analysis of Genetic Association Studies. [PDF]

Brain Behav
Jenwitheesuk A, Pabalan N, Tapanadechopone P, Jarjanazi H, Arunphalungsanti K, Tharabenjasin P.   +5 more
europepmc   +1 more source

Brain-Derived Neurotrophic Factor Induces Long-Term Potentiation in Intact Adult Hippocampus: Requirement for ERK Activation Coupled to CREB and Upregulation of Arc Synthesis

Journal of Neuroscience, 2002
S. Ying, M. Futter, K. Rosenblum, M. Webber, S. Hunt, T. Bliss, C. Bramham   +6 more
semanticscholar   +1 more source

SGLT2 Inhibition by Enavogliflozin Significantly Reduces Aβ Pathology and Restores Cognitive Function via Upregulation of Microglial AMPK Signaling in 5XFAD Mouse Model of Alzheimer's Disease

Aging Cell, EarlyView.
SGLT2 inhibition with Enavogliflozin significantly improves cognitive function and reduces Aβ pathology in the 5XFAD mouse model of Alzheimer's disease. Through AMPK activation, Enavogliflozin enhances microglial mitochondrial function and Aβ phagocytosis while reducing neuroinflammation.
Jihui Han, Jaehoon Song, Eun Sun Jung, Ji Won Choi, Hye Young Ji, Inhee Mook‐Jung   +5 more
wiley   +1 more source

Effect of negative mood, serum inflammatory factors, miR-155, and brain-derived neurotrophic factor. [PDF]

World J Psychiatry
Zhang Q, Zhao Y, Cheng GY.
europepmc   +1 more source

Acute effects of brain-derived neurotrophic factor on energy expenditure in obese diabetic mice

, 2001
Atsushi Tsuchida, Takeshi Nonomura, Michiko Ono‐Kishino, Tsutomu Nakagawa, Mutsuo Taiji, Hiroshi Noguchi   +5 more
openalex   +1 more source

Cognitive and Psychomotor Processing Speed in Medication‐Naïve Individuals With First‐Episode of Psychosis: The Role of Peripheral Inflammatory Markers

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Background and Hypothesis Deficits in processing speed (PS) and psychomotor speed (PMS) are core cognitive impairments in schizophrenia spectrum disorders, including first‐episode psychosis (FEP). Neuroinflammation has been proposed as a potential contributor to these deficits.
Ángel Yorca‐Ruiz, Carlos Martínez Asensi, Rebeca Magdaleno Herrero, Alexandre Díaz‐Pons, Víctor Ortiz‐García de la Foz, Luis Manuel Fernández Cacho, Ana Catalán Alcantara, Benedicto Crespo‐Facorro, Rosa Ayesa‐Arriola   +8 more
wiley   +1 more source