Results 301 to 310 of about 236,444 (370)

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam   +12 more
wiley   +1 more source

Effect of brain-derived neurotrophic factor on the release of substance P from rat spinal cord

open access: bronze, 2001
Annegret Meyer-Tuve   +4 more
openalex   +1 more source

Mathematical Modeling of Neuroinflammation in Neurodegenerative Diseases

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Age‐related neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD) and Parkinson's disease (PD) are an increasing public health concern. Whereas the pathology of these diseases is complex, chronic central inflammation, or neuroinflammation, is commonly observed across many neurodegenerative diseases ...
Alex Foster‐Powell   +4 more
wiley   +1 more source

Serum Brain-Derived Neurotrophic Factor: An Emerging Marker for Diabetic Retinopathy. [PDF]

open access: yesCureus
K U VR   +7 more
europepmc   +1 more source

Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation

open access: yesSensory Neuroscience, EarlyView.
ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera   +3 more
wiley   +1 more source

Conductive Materials and Electrical Stimulation for Auditory Restoration

open access: yesSensory Neuroscience, EarlyView.
Applications of electroconductive biomaterials and electrical stimulation in cochlear tissue engineering.(1) Enable auditory neural repair through conductive materials and electrical stimulation, enhancing neuron survival and synaptic plasticity.(2) Integrate optogenetic‐electrical systems and cochlear organoid platforms for frequency‐specific ...
Menghui Liao   +8 more
wiley   +1 more source

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