Results 51 to 60 of about 4,489,782 (294)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Brain-Computer Interface for robotic arm control [PDF]

, 2011
Lenhardt A. A Brain-Computer Interface for robotic arm control. Bielefeld: Universität Bielefeld; 2011.Brain-Computer Interfaces (BCI) are tools that open a new channel of communication between humans and machines.
Lenhardt, Alexander
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

BRAIN COMPUTER INTERFACE - Application of an Adaptive Bi-stage Classifier based on RBF-HMM [PDF]

, 2010
Brain Computer Interface is an emerging technology that allows new output paths to communicate the users intentions without the use of normal output paths, such as muscles or nerves. In order to obtain their objective, BCI devices make use of classifiers
Barrientos Cruz, Antonio, Pérez Martínez, Jose Luis   +1 more
core  

Future developments in brain-machine interface research [PDF]

, 2011
Neuroprosthetic devices based on brain-machine interface technology hold promise for the restoration of body mobility in patients suffering from devastating motor deficits caused by brain injury, neurologic diseases and limb loss. During the last decade,
Andrew M. Fuller, Nicolelis, Miguel A. L., Je Hi An, Jesse A. Winans, Fuller, Andrew M., Mikhail A. Lebedev, Lebedev, Mikhail A., Schwarz, David A., Andrew J. Tate, Katie Z. Zhuang, Miguel A. L. Nicolelis, Peter J. Ifft, Li, Zheng, Fitzsimmons, Nathan A., Zheng Li, Ifft, Peter J., Timothy L. Hanson, An, Je Hi, Winans, Jesse A., David A. Schwarz, Zhuang, Katie Z., Joseph E. O'Doherty, Tate, Andrew J., O\u27Doherty, Joseph E., Nathan A. Fitzsimmons, Hanson, Timothy L.   +25 more
core   +1 more source

Denoising Non-Invasive Electroespinography Signals by Different Cardiac Artifact Removal Algorithms

Biosensors
The non-invasive recording of spinal cord neuronal activity, also known as electrospinography (ESG), using high-density surface electromyography (HD-sEMG) is a promising emerging biosensing modality.
Desirée I. Gracia, Eduardo Iáñez, Mario Ortiz, José M. Azorín   +3 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Effects of tDCS on Real-Time BCI Detection of Pedaling Motor Imagery

Sensors, 2018
The purpose of this work is to strengthen the cortical excitability over the primary motor cortex (M1) and the cerebro-cerebellar pathway by means of a new transcranial direct current stimulation (tDCS) configuration to detect lower limb motor imagery ...
Maria de la Soledad Rodriguez-Ugarte, Eduardo Iáñez, Mario Ortiz-Garcia, José M. Azorín   +3 more
doaj   +1 more source

Development of split-force-controlled body weight support (SF-BWS) robot for gait rehabilitation

Frontiers in Human Neuroscience, 2023
This study introduces a body-weight-support (BWS) robot actuated by two pneumatic artificial muscles (PAMs). Conventional BWS devices typically use springs or a single actuator, whereas our robot has a split force-controlled BWS (SF-BWS), in which two ...
Asuka Takai, Asuka Takai, Tatsuya Teramae, Tomoyuki Noda, Koji Ishihara, Jun-ichiro Furukawa, Jun-ichiro Furukawa, Hiroaki Fujimoto, Megumi Hatakenaka, Nobukazu Fujita, Akihiro Jino, Yuichi Hiramatsu, Ichiro Miyai, Jun Morimoto, Jun Morimoto, Jun Morimoto   +15 more
doaj   +1 more source