Results 101 to 110 of about 8,779,803 (385)

Methodology to derive preference for health screening programmes using discrete choice experiments: a scoping review

BMC Health Services Research, 2022
Background While involving users in healthcare decision-making has become increasingly common and important, there is a lack of knowledge about how to best design community-based health screening programs.
David Brain, Amarzaya Jadambaa, Sanjeewa Kularatna   +2 more
doaj   +1 more source

A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury. [PDF]

, 2016
The p75 neurotrophin receptor is important in multiple physiological actions including neuronal survival and neurite outgrowth during development, and after central nervous system injury.
Alam, Antoine, Arnone, Michele, Baroni, Marco, Beattie, Michael S, Bono, Françoise, Bresnahan, Jacqueline C, Canolle, Benoit, Castel, Marie-Noelle, Delbary-Gossart, Sandrine, Delesque-Touchard, Nathalie, Ferguson, Adam R, Ferzaz, Badia, Herbert, Jean-Marc, Laboudie, Patricia, Lamarche, Isabelle, Lee, Sangmi, Lin, Amity, Manley, Geoffrey T, Sacramento, Jeffrey, Salegio, Ernesto A, Savi, Pierre   +20 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Textos cosmogónico-religiosos de las civilizaciones nahuas y españolas: narrativas inestables como ejes simbólicos de sistemas de comunicación socializadores Cosmogonic-ReligiousTexts of the Nahua, Mixtee and Spanish Civilizations: Unstable Narratives as Symbolic Referents within Socializing Systems of Communication

Aisthesis, 2010
En la España del siglo XVI, las narrativas cosmogónico-religiosas se mantenían, físicamente, usando el sistema alfabético romano. Entre los nahuas y mixtecas, estas historias se mantenían usando un sistema pictográfico. Este artículo discutirá el tema de
Cecilia Brain
doaj  

The role of the ventrolateral frontal cortex in inhibitory oculomotor control [PDF]

, 2007
It has been proposed that the inferior/ventrolateral frontal cortex plays a critical role in the inhibitory control of action during cognitive tasks.However, the contribution of this region to the control of eye movements has not been clearly established.
Chamberlain, Marcia, Gutowski, Nicholas, Hodgson, Tim, Husain, Masud, James, Martin, Kennard, Christopher, Parris, Benjamin   +6 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

The contribution of Raymond Dart to the development of cave taphonomy [PDF]

, 1997
Main articleThe basic principles of African cave taphonomy were formulated in 1976, but twenty years earlier, Raymond Dart embarked on a pioneering taphonomic investigation into a hominid-bearing fossil assemblage from the Makapansgat Limeworks cave ...
Brain
core  

Motor recovery following capsular stroke [PDF]

, 1993
The functional anatomy of motor recovery was studied by assessing motor function quantitatively in 23 patients following capsular or striatocapsular stroke.
Danek, Adrian, Fries, Wolfgang, Hamburger, C., Scheidtmann, K.   +3 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

The Christian Environmental Ethic of the Russian Pomor

Ecozon@, 2011
This article revisits Lynn White's famous 1967 article that placed the blame forenvironmental problems in the Western world on the Judeo-Christian belief system, anddiscusses the case of the Pomor, a Russian sub-ethnicity who settled on the shores ofthe ...
Stephen Brain
doaj