ABSTRACT Objective Spinocerebellar ataxias (SCAs) are a group of genetically heterogeneous neurodegenerative diseases causing progressive deterioration and reduced quality of life. Therapeutic advances have been limited by a lack of sensitive anatomic, functional, or diffusion imaging‐based biomarkers.
David J. Arpin+11 more
wiley +1 more source
Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro+12 more
wiley +1 more source
Observations on the ALTERATION OF THE CIRCULATION OF THE BRAIN BY SURGICAL MEANS IN DISEASES OF THE CENTRAL NERVOUS SYSTEM [PDF]
N. D. Royle
openalex +1 more source
Unraveling consistently altered brain activations of language deficits in schizophrenia: evidence from ALE meta-analysis. [PDF]
He Y+5 more
europepmc +1 more source
Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu+13 more
wiley +1 more source
INCREASE OF 5-HYDROXYTRYPTAMINE IN THE RAT BRAIN BY RAUNESCINE [PDF]
M. K. Paasonen, Niilo T. Kärki
openalex +1 more source
Nanoparticle‑based delivery systems for targeted therapy in brain tumors: Progress, challenges and perspectives (Review). [PDF]
Si JX, Liu ZC, Gu F, Jin X, Ma YY.
europepmc +1 more source
Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova+5 more
wiley +1 more source
Fluid Flow Measurement in the Mid-1970's
T. J. S. Brain
doaj +1 more source