Results 71 to 80 of about 2,890,246 (202)

Brain age predicts mortality [PDF]

Molecular Psychiatry, 2017
Age-associated disease and disability are placing a growing burden on society. However, ageing does not affect people uniformly. Hence, markers of the underlying biological ageing process are needed to help identify people at increased risk of age-associated physical and cognitive impairments and ultimately, death.
Cole, J. H., Ritchie, S. J., Bastin, M. E., Valdes Hernandez, M. C., Munoz Maniega, S., Royle, N., Corley, J., Pattie, A., Harris, S. E., Zhang, Q., Wray, N. R., Redmond, P., Marioni, R. E., Starr, J. M., Cox, S. R., Wardlaw, J. M., Sharp, D. J., Deary, I. J.   +17 more
openaire   +8 more sources

Longitudinal analysis of the developing rhesus monkey brain using magnetic resonance imaging: birth to adulthood. [PDF]

, 2016
We have longitudinally assessed normative brain growth patterns in naturalistically reared Macaca mulatta monkeys. Postnatal to early adulthood brain development in two cohorts of rhesus monkeys was analyzed using magnetic resonance imaging.
Amaral, David G, Bauman, Melissa D, Buonocore, Michael H, Fletcher, Evan, Grayson, David, Lee, Aaron, Schumann, Cynthia Mills, Scott, Julia A   +7 more
core   +1 more source

Mediating role of muscle quality in the liver–brain axis: integrated analysis of CT markers of body composition, brain aging, and biomarkers

Frontiers in Aging Neuroscience
BackgroundThe liver, skeletal muscle, and brain are interconnected through metabolic and endocrine pathways, constituting a systemic axis that may influence neurodegeneration.
Minchul Kim, Chongwon Pae, Joon Ho Moon, Joon Ho Moon, Inpyeong Hwang, Inpyeong Hwang, Kyu Sung Choi, Kyu Sung Choi   +7 more
doaj   +1 more source

Normative Modeling Reveals Age‐Atypical Cortical Thickness Differences Between Hepatic Steatosis and Fibrosis in Non‐Alcoholic Fatty Liver Disease

Brain and Behavior
Objectives: To investigate individual variations and outliers in cortical thickness among non‐alcoholic fatty liver disease (NAFLD) patients, ranging from hepatic steatosis to fibrosis, using neuroanatomical normative modeling.
Minchul Kim, Inpyeong Hwang, Kyu Sung Choi, Junhyeok Lee, Minjung Ryu, Jung Hyun Park, Joon Ho Moon   +6 more
doaj   +1 more source

Brain Age Prediction of Children Using Routine Brain MR Images via Deep Learning

Frontiers in Neurology, 2020
Predicting brain age of children accurately and quantitatively can give help in brain development analysis and brain disease diagnosis. Traditional methods to estimate brain age based on 3D magnetic resonance (MR), T1 weighted imaging (T1WI), and ...
Jin Hong, Jin Hong, Zhangzhi Feng, Shui-Hua Wang, Shui-Hua Wang, Andrew Peet, Yu-Dong Zhang, Yu-Dong Zhang, Yu Sun, Yu Sun, Ming Yang   +10 more
doaj   +1 more source

Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. [PDF]

, 2009
The cause(s) of sporadic Alzheimer's disease (sAD) are complex and currently poorly understood. They likely result from a combination of genetic, environmental, proteomic and lipidomic factors that crucially occur only in the aged brain.
Green, Kim N
core   +1 more source

Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. [PDF]

, 2013
Discrete time survival analysis was used to assess the age-specific association of event-related oscillations (EROs) and CHRM2 gene variants on the onset of regular alcohol use and alcohol dependence.
Almasy, Laura, Bauer, Lance, Bierut, Laura, Bucholz, Kathleen, Chorlian, David B, Dick, Danielle, Edenberg, Howard J, Foroud, Tatiana, Goate, Alison, Hesselbrock, Victor, Kang, Sun J, Kramer, John, Kuperman, Sam, Manz, Niklas, Nurnberger, John, Porjesz, Bernice, Rangaswamy, Madhavi, Rice, John, Schuckit, Marc, Tischfield, Jay, Wang, Jen-Chyong   +20 more
core   +2 more sources

Insulin and brain aging

Menopausal Review, 2017
The world's population is living much longer than in the past. It is crucial to find as many pathological factors that deteriorate the health condition and well-being of elderly people as possible. Loss of activity and functions over time is typical for elderly people.
Agnieszka Baranowska-Bik, Wojciech Bik
openaire   +3 more sources

Ageing and the brain [PDF]

Postgraduate Medical Journal, 2006
Abstract Ageing causes changes to the brain size, vasculature, and cognition. The brain shrinks with increasing age and there are changes at all levels from molecules to morphology. Incidence of stroke, white matter lesions, and dementia also rise with age, as does level of memory impairment and there are changes in levels of ...
openaire   +2 more sources

Ageing and the brain

The Journal of Pathology, 2007
AbstractIn this review, the evidence for changes in the human brain with ageing at both the macroscopic and microscopic levels is summarized. Loss of neurons is now recognized to be more modest than initial studies suggested and only affects some neuron populations. Accompanying loss of neurons is some reduction in the size of remaining neurons.
openaire   +3 more sources