Results 71 to 80 of about 2,910,945 (298)

Epilepsy is associated with the accelerated aging of brain activity in sleep

Frontiers in Physiology
ObjectiveAlthough seizures are the cardinal feature, epilepsy is associated with other forms of brain dysfunction including impaired cognition, abnormal sleep, and increased risk of developing dementia.
Peter N. Hadar, Mike Westmeijer, Mike Westmeijer, Haoqi Sun, Erik-Jan Meulenbrugge, Jin Jing, Luis Paixao, Ryan A. Tesh, Madalena Da Silva Cardoso, Pierrick Arnal, Rhoda Au, Chol Shin, Chol Shin, Soriul Kim, Robert J. Thomas, Sydney S. Cash, M. Brandon Westover   +16 more
doaj   +1 more source

Inflammation and Brain Aging

Annals of the Russian academy of medical sciences, 2015
The review covers current concepts on cell and molecular mechanisms of neuroinflammation and aging with the special focus on the regulation of cytokine-producing activity of astroglial cells and intercellular communication. The review reflects that a key component of the aging phenomenon as a result of ineffective implementation of anti-inflammatory ...
A B, Salmina, Yu K, Komleva, N V, Kuvacheva, O L, Lopatina, E A, Pozhilenkova, Ya V, Gorina, E L, Gasymly, Yu A, Panina, A V, Morgun, N A, Malinovskaya   +9 more
openaire   +3 more sources

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

A predictive model of Parkinsonian brain aging based on brain imaging features

Frontiers in Neurology
IntroductionThis study explores the use of imaging to evaluate brain aging to establish a model for predicting brain age in patients with Parkinson’s disease.MethodsStructural brain MRI data from 345 healthy individuals were obtained from the IXI ...
Xiaoyan Zhou, Xiaoyan Zhou, Xiaoyan Zhou, Haoyong Zhu, Xiaoming Wang, Xiaoming Wang, Qing Gao   +6 more
doaj   +1 more source

Ensemble Learning of Convolutional Neural Network, Support Vector Machine, and Best Linear Unbiased Predictor for Brain Age Prediction: ARAMIS Contribution to the Predictive Analytics Competition 2019 Challenge

Frontiers in Psychiatry, 2020
We ranked third in the Predictive Analytics Competition (PAC) 2019 challenge by achieving a mean absolute error (MAE) of 3.33 years in predicting age from T1-weighted MRI brain images.
Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Baptiste Couvy-Duchesne, Johann Faouzi, Johann Faouzi, Johann Faouzi, Johann Faouzi, Johann Faouzi, Benoît Martin, Benoît Martin, Benoît Martin, Benoît Martin, Benoît Martin, Elina Thibeau–Sutre, Elina Thibeau–Sutre, Elina Thibeau–Sutre, Elina Thibeau–Sutre, Elina Thibeau–Sutre, Adam Wild, Adam Wild, Adam Wild, Adam Wild, Adam Wild, Manon Ansart, Manon Ansart, Manon Ansart, Manon Ansart, Manon Ansart, Stanley Durrleman, Stanley Durrleman, Stanley Durrleman, Stanley Durrleman, Stanley Durrleman, Didier Dormont, Didier Dormont, Didier Dormont, Didier Dormont, Didier Dormont, Didier Dormont, Ninon Burgos, Ninon Burgos, Ninon Burgos, Ninon Burgos, Ninon Burgos, Olivier Colliot, Olivier Colliot, Olivier Colliot, Olivier Colliot, Olivier Colliot   +51 more
doaj   +1 more source

Brain age predicts mortality [PDF]

Molecular Psychiatry, 2017
Age-associated disease and disability are placing a growing burden on society. However, ageing does not affect people uniformly. Hence, markers of the underlying biological ageing process are needed to help identify people at increased risk of age-associated physical and cognitive impairments and ultimately, death.
Cole, J. H., Ritchie, S. J., Bastin, M. E., Valdes Hernandez, M. C., Munoz Maniega, S., Royle, N., Corley, J., Pattie, A., Harris, S. E., Zhang, Q., Wray, N. R., Redmond, P., Marioni, R. E., Starr, J. M., Cox, S. R., Wardlaw, J. M., Sharp, D. J., Deary, I. J.   +17 more
openaire   +8 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Structural subnetwork evolution across the life-span: rich-club, feeder, seeder

, 2018
The impact of developmental and aging processes on brain connectivity and the connectome has been widely studied. Network theoretical measures and certain topological principles are computed from the entire brain, however there is a need to separate and ...
A Zalesky, AW Chung, D Batalle, D Batalle, DJ Watts, DS Bassett, DS Grayson, E Bullmore, E Bullmore, G Ball, G Collin, JA Brown, KB Nooner, L Bonilha, M Cao, M Daianu, M Ingalhalikar, M Rubinov, MN Moussa, MP Heuvel van den, MP Heuvel Van Den, O Sporns, O Sporns, O Sporns, O Sporns, O Tymofiyeva, P Hagmann, RC Craddock, S Mori, S Ray, T Opsahl, T Zhao   +31 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

The role of EGFR mutation as a prognostic factor in survival after diagnosis of brain metastasis in non-small cell lung cancer: A systematic review and meta-analysis [PDF]

, 2019
Background The brain is a common site for metastasis in non-small-cell lung cancer (NSCLC). This study was designed to evaluate the relationship between the mutational of the epidermal growth factor receptor (EGFR) and overall survival (OS) in NSCLC ...
Han, Yunan, Li, Wen-Ya, Liu, Xing-Yu, Miao, Zhi-Feng, Song, Yong-Xi, Wang, Zhen-Ning, Wu, Jian-Hua, Xu, Hao, Xu, Hui-Mian, Xu, Ying-Ying, Yin, Song-Cheng, Zhao, Ting-Ting   +11 more
core   +2 more sources