Results 151 to 160 of about 2,163,819 (261)

Sparse representation learning derives biological features with explicit gene weights from the Allen Mouse Brain Atlas. [PDF]

PLoS One, 2023
Abbasi M, Sanderford CR, Raghu N, Pasha M, Bartelle BB.   +4 more
europepmc   +1 more source

Probing the Energy Landscape of α‐Synuclein Amyloid Fibril Formation by Systematic K‐to‐Q Mutagenesis

Advanced Science, EarlyView.
We use lysine‐to‐glutamine mutations to study the effect of electrostatics on the kinetics and thermodynamics of alpha‐synuclein amyloid fibril formation. We find that mutational effects map on their structural context within fibrils and identify residues that modulate the energy landscape of alpha‐synuclein self‐assembly. Our work outlines a scalable,
Antonin Kunka, Azad Farzadfard, Jacob Aunstrup Larsen, Rasmus Krogh Norrild, Federica Saraceno, Celia Fricke, Hossein Mohammad‐Beigi, Ahmed Sadek, Jonas Folke, Susana Aznar, Alexander K. Buell   +10 more
wiley   +1 more source

Application of the Allen Human Brain Atlas in Alzheimer's disease and Parkinson's disease. [PDF]

Transl Neurodegener
Xiao Y, Wang S, Hou Y, Shang H.
europepmc   +1 more source

Author Correction: The Brain/MINDS 3D digital marmoset brain atlas. [PDF]

Sci Data, 2022
Woodward A, Hashikawa T, Maeda M, Kaneko T, Hikishima K, Iriki A, Okano H, Yamaguchi Y.   +7 more
europepmc   +1 more source

Expanding Genetic Code to Generate Human Brain Organoids with Both Vasculature and Microglia‐Like Cells

Advanced Science, EarlyView.
Using genetic code expansion, we engineered vascularized human cerebral organoids (vhCOs) with microglia‐like cells and blood‐brain barrier features. vhCOs recapitulate neurovascular interactions, regional identities, and neuronal subtypes resembling the fetal brain.
Haishuang Lin, Yaqing Wang, Hu Du, Yuxin Qin, Haoyu Zhang, Peng Wang, Lin Wei, Jianhua Qin   +7 more
wiley   +1 more source

Non-parametric MRI Brain Atlas for the Polish Population. [PDF]

Front Neuroinform, 2021
Borys D, Kijonka M, Psiuk-Maksymowicz K, Gorczewski K, Zarudzki L, Sokol M, Swierniak A.   +6 more
europepmc   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source

Language mapped to a high-resolution brain atlas for surgical evaluation of epilepsy patients. [PDF]

Epilepsia
Watson EM, Collins E, Chishti O, Bose-Roy R, McGrath H, Akierman Segal N, Lehman R, Sivaraju A, Zaveri HP, Spencer DD.   +9 more
europepmc   +1 more source

ATLAS Physics Briefing: Boosting precision of top-quark mass measurement with ATLAS

Figures accompanying the briefing, "Boosting precision of top-quark mass measurement with ...
ATLAS Collaboration
core  

CERN OpenDays 2019 - ATLAS Visit Points & Activities

, 2019
Photos from the CERN Open Days 2019 taken by ATLAS volunteers (individual photographer credits in file name/caption)
ATLAS Collaboration
core