SDS‐CRISPR for Single‐Nucleotide Variant Detection
Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan +12 more
wiley +1 more source
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä +18 more
wiley +1 more source
An Augmented Reality-Based Navigation System for Stereotactic Brain Biopsy with Multi-Objective Path Planning and Hybrid Registration. [PDF]
Zhang T +5 more
europepmc +1 more source
Brain biopsy in patients with CLIPPERS syndrome: why and when. [PDF]
Galazky I +5 more
europepmc +1 more source
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Accuracy of frameless stereotactic brain biopsy: a retrospective cohort study with MRI-only and MRI-CT fusion navigation. [PDF]
Meinert F +5 more
europepmc +1 more source
Abundant infiltration of B cells and plasma cells in brain biopsy of a male patient with severe anti-NMDA receptor encephalitis: A case report. [PDF]
Wei L, Lu Z, Du Z, Wang Y, Guan H.
europepmc +1 more source
A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun +12 more
wiley +1 more source
It Is Not Always Metastasis: A Case Report of a Primary Nervous System Anaplastic Large Cell Lymphoma and the Relevance of Brain Biopsy. [PDF]
Salinas D +4 more
europepmc +1 more source

