Results 161 to 170 of about 270,863 (296)

SDS‐CRISPR for Single‐Nucleotide Variant Detection

open access: yesAdvanced Science, EarlyView.
Structure‐disruption‐sensitive CRISPR (SDS‐CRISPR) converts structural instability into single‐nucleotide precision, thereby overcoming mismatch tolerance in canonical Cas12a and enabling versatile diagnostics across DNA, RNA, and microRNA targets. When applied to rapid IDH1 mutation detection for glioma genotyping and integrated with lateral‐flow ...
Xin Guan   +12 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä   +18 more
wiley   +1 more source

Brain biopsy in patients with CLIPPERS syndrome: why and when. [PDF]

open access: yesTher Adv Neurol Disord, 2022
Galazky I   +5 more
europepmc   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

Accuracy of frameless stereotactic brain biopsy: a retrospective cohort study with MRI-only and MRI-CT fusion navigation. [PDF]

open access: yesActa Neurochir (Wien)
Meinert F   +5 more
europepmc   +1 more source

A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun   +12 more
wiley   +1 more source

Procurement of liver allografts from non-heart beating donors [PDF]

open access: yes, 1990
Demetris, AJ   +5 more
core  

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