Results 101 to 110 of about 627,989 (344)

Establishment and genetic characterization of zebrafish RW line

open access: yesScientific Reports
Zebrafish have emerged as an alternative vertebrate model for both basic and applied science. While two zebrafish lines, AB and TU, have been extensively used, recent studies suggest that complex behaviors and susceptibility to adult phenotypes vary ...
Kenichiro Sadamitsu   +7 more
doaj   +1 more source

Architectural Education in Relation with Thinking Preferences of Students [PDF]

open access: yesصفه, 2017
Because of the multiple dimensions of design issues, it is essential that architectural students as designers be trained in objective, subjective, critical, and creative thinking styles.
Hani Mansurnejad
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease [PDF]

open access: yes, 2012
A significant amount of evidence suggests that the p38-mitogen-activated protein kinase (MAPK) signalling cascade plays a crucial role in synaptic plasticity and in neurodegenerative diseases.
Corrêa, Sônia A. L.   +1 more
core   +3 more sources

Carbon Dots: A Future Blood–Brain Barrier Penetrating Nanomedicine and Drug Nanocarrier

open access: yesInternational Journal of Nanomedicine, 2021
Wei Zhang,1,* Ganesh Sigdel,1,* Keenan J Mintz,1 Elif S Seven,1 Yiqun Zhou,1 Chunyu Wang,2,3 Roger M Leblanc1 1Department of Chemistry, University of Miami, Coral Gables, FL, 33146, USA; 2Department of Biological Sciences, Rensselaer Polytechnic ...
Zhang W   +6 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Electroconvulsive Therapy

open access: yesمجله دانشکده پزشکی اصفهان, 2008
Electroconvulsive therapy (ECT) is a procedure in which electric currents are passed through the brain, deliberately triggering a brief seizure. This seems to cause changes in brain chemistry that can alleviate symptoms of certain mental illnesses ECT ...
Mahmoud Rafieian Kopaei   +1 more
doaj  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes

open access: yesScientific Reports, 2017
γ-Aminobutyric acid type A (GABAA) receptors are pentameric GABA-gated chloride channels that are, in mammalians, drawn from a repertoire of 19 different genes, namely α1-6, β1-3, γ1-3, δ, ε, θ, π and ρ1-3.
Xenia Simeone   +12 more
doaj   +1 more source

Factors influencing cerebral plasticity in the normal and injured brain

open access: yesFrontiers in Human Neuroscience, 2010
An important development in behavioural neuroscience in the past 20 years has been the demonstration that it is possible to stimulate functional recovery after cerebral injury in laboratory animals.
Bryan Kolb, Campbell Teskey, Robbin Gibb
doaj   +1 more source

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