Results 151 to 160 of about 353,130 (267)

Chronic cocaine enhances release of neuroprotective amino acid taurine: a microdialysis study

, 2008
Cocaine inhibits high-affinity neurotransmitter uptake at the presynaptic nerve terminals to increase synaptic levels of dopamine, norepinephrine and serotonin^1^. This increase of synaptic dopamine may cause neurotoxicity^2,3^.
Theodore Lidsky, Shailesh Banerjee, Elena Yablonski-Alter, Eleonora Gashi, Mervan Agovic, Eitan Freedman   +5 more
core   +1 more source

Exploring the Research Progress of Vascular Dementia and Key Regulatory Molecules: E2F1. [PDF]

Int J Mol Sci
Zhang F, Hao Z, Song M, Zhao Z, Li W, Chen J.   +5 more
europepmc   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Measurement of brain volume using MRI:software, techniques, choices and prerequisites

, 2010
Magnetic resonance imaging (MRI) permits in vivo quantification of brain compartment volume, and has many applications in cognitive, clinical and comparative neuroscience.
Keller, Simon S., Roberts, Neil
core  

Exploring the gut-brain axis: dietary influences on Alzheimer's disease pathogenesis. [PDF]

Front Microbiomes
Mansour SR, Khalaf MA, Moustafa MA, Moustafa MA, Moustafa AA.   +4 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Plasma biomarkers in chronic single moderate–severe traumatic brain injury

Blood biomarkers are an emerging diagnostic and prognostic tool that reflect a range of neuropathological processes following traumatic brain injury (TBI).
Rowe, C, Shultz, SR, O’Brien, WT, Spitz, G, Dore, V, Hicks, AJ, Ponsford, JL, Vivash, L, Krishnadas, N, O’Brien, TJ, Law, M, McDonald, SJ   +11 more
core   +1 more source

Chronic lead encephalopathy in an adult: A case report and literature review. [PDF]

Clin Park Relat Disord
Rim T, Asmaa S, Hajar K, Kamal H, Salma B, Bouchra EM, Rafai MA, Hicham EO.   +7 more
europepmc   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Functional MRI with active, fully implanted, deep brain stimulation systems: Safety and experimental confounds

, 2007
We investigated safety issues and potential experimental confounds when performing functional magnetic resonance imaging (fMRI) investigations in human subjects with fully implanted, active, deep brain stimulation (DBS) systems.
Lemieux, L., Thornton, John, Yousry, Tarek, Thobois, S., Pinto, Serge, Allen, P.J., Lemieux, Louis, Carmichael, David, Limousin-Dowsey, Patricia, Pinto, S., Limousin-Dowsey, P., Thornton, J.S., Thobois, Stéphane, Carmichael, D.W., Yousry, T., Allen, Philip   +15 more
core