Results 151 to 160 of about 4,538,394 (284)

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

A Comparison of postoperative hemodynamic trajectories in donation after brain death versus circulatory death heart transplantation. [PDF]

JHLT Open
Petrovic M, Eidson C, Wang CC, Navid W, Ahmad A, McGann K, Williams AM, Trahanas J, Bommareddi S, Absi T, Quintana E, Rali AS, Schlendorf KH, Bacchetta M, Shah AS, Lima B.   +15 more
europepmc   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Curriculum Innovation: A Multicenter Feasibility Study of a Consensus-Based Brain Death Simulation Curriculum. [PDF]

Neurol Educ
Elmashala A, Albin CSW, Harrison DS, Koffman L, Zhou X, LaBuzetta JN, Beekman RB, Cappucci SP, Bevers M, Kamdar H, Hoerth MT, Lewis A, Wahlster S, Cormier J, Ford J, Greer DM, Morris NA, for CRESCENT Collaboration.   +17 more
europepmc   +1 more source

Personal Identity and Brain Death: A Critical Response

, 1986
The authors contend that there are logical inconsistencies in a theory put forth by Michael Green and Daniel Wikler ("Brain death and personal identity,
Jones, Royce P., Agich, George J.
core  

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Determination of Brain Death/Death by Neurologic Criteria in Adults: A Structured Framework for Medical Educators. [PDF]

Neurol Educ
Cormier J, Marinelli S, Albin CSW, Morris NA, Lewis A, Beekman RB, Greer DM, Wahlster S, Town JA.   +8 more
europepmc   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Distinct goal-directed perfusion signatures in donation after brain death versus circulatory death heart transplantation. [PDF]

JHLT Open
Wang CC, Ahmad A, Petrovic M, McGann K, Williams A, Trahanas J, Bommareddi S, Absi T, Quintana E, Rali A, Schlendorf K, Bacchetta M, Shah A, Lima B.   +13 more
europepmc   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source