Results 61 to 70 of about 1,696,584 (309)

Innate Immune Cells Activating Receptors Are Crucial Factors Regulating Inflammation and Cell Death in Traumatic Brain Injury [PDF]

, 2023
Xudong Zhou, Jingjing He, Aochun Yue, Huiping Song, Xuhan Liu, Wei Han, Qin Li   +6 more
openalex   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

FEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel, Mekala Gunasekaran, Audrey L. Daugherty, Natalya M. Wells, Johnnie Turner, Christine C. Bruels, Christina A. Pacak, Isabelle Draper, Peter B. Kang   +8 more
wiley   +1 more source

Deceased organ donation of foreign nationals in India

Indian Journal of Transplantation, 2019
Inward foreign tourism in India is on the rise and the tourists are equally at risk of fatal road accidents and stroke leading to brain death. This provides an opportunity for organ donation; however, no guidelines are available on how to proceed in such
Pallavi Kumar, Sunil Shroff, Sumana Navin, Muneet Kaur Sahi, Jaya Jairam, Surendra Kumar Mathur, Anant Kumar, Darius Mirza, Subba B Rao, Gunadhar Padhi   +9 more
doaj   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

On Evolution of God-Seeking Mind: An Inquiry Into Why Natural Selection Would Favor Imagination and Distortion of Sensory Experience [PDF]

, 2002
The earliest known products of human imagination appear to express a primordial concern and struggle with thoughts of dying and of death and mortality.
Montell, Conrad
core  

Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: Implication for neuroprotective therapies [PDF]

, 2013
Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain ...
Alberch, J., Brito, V., Del Toro Ruiz, D., Gines, S., Giralt, A., Puigdellivol, M.   +5 more
core   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Pobieranie narządów po zatrzymaniu krążenia. O nadrzędności neurologicznego kryterium śmierci nad krążeniowym – kwestie filozoficzne

Analiza i Egzystencja, 2018
DONATION AFTER CIRCULATORY DETERMINATION OF DEATH. ABOUT THE PRECEDENCE OF NEUROLOGICAL CRITERION OF DEATH OVER CIRCULATORY CRITERION – PHILOSOPHICAL ISSUES Summary This two-part article concerns with bioethical issues associated with organ donation
Piotr Nowak
doaj   +1 more source

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Brain Death in Islamic Jurisprudence

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2016
BACKGROUND AND OBJECTIVE: In today's world, Islamic jurisprudence encounters  new issues. One of the areas where jurisprudence gets involved is the issues concerned with brain death, whether brain death in jurisprudence and Islamic law is considered the ...
A Nikzad, GA Jorsaraei
doaj