Results 31 to 40 of about 2,638,617 (370)
Brain edema : a valid endpoint for measuring hepatic encephalopathy? [PDF]
, 2016 Hepatic encephalopathy (HE) is a major complication of liver failure/disease which frequently develops during the progression of end-stage liver disease.
Bémeur, Chantal +5 more
core +1 more source
Is Addiction a Brain Disease? [PDF]
Neuroethics, 2016 Where does normal brain or psychological function end, and pathology begin? The line can be hard to discern, making disease sometimes a tricky word. In addiction, normal 'wanting' processes become distorted and excessive, according to the incentive-sensitization theory.
openaire +3 more sources
Cells, 2020 Neuroinflammation and cell death are among the common symptoms of many central nervous system diseases and injuries. Neuroinflammation and programmed cell death of the various cell types in the brain appear to be part of these disorders, and ...
Jasmina Dimitrova-Shumkovska +2 more
doaj +1 more source
A model of brain morphological changes related to aging and Alzheimer's disease from cross-sectional assessments [PDF]
, 2019 In this study we propose a deformation-based framework to jointly model the influence of aging and Alzheimer's disease (AD) on the brain morphological evolution.
Ayache, Nicholas +4 more
core +4 more sources
Nature Communications, 2022 In this work, Louros et al. uncover a rule book for interactions of amyloids with other proteins. This grammar was shown to promote cellular spreading of tau aggregates in cells, but can also be harvested to develop structure-based aggregation blockers.
Nikolaos Louros +12 more
doaj +1 more source
Application of Time-Aware PC algorithm to compute Causal Functional Connectivity in Alzheimer's Disease from fMRI data [PDF]
arXiv, 2023 Functional Connectivity between brain regions is known to be altered in Alzheimer's disease, and promises to be a biomarker for early diagnosis of the disease. While several approaches for functional connectivity obtain an un-directed network representing stochastic associations (correlations) between brain regions, association does not necessarily ...
arxiv
Alois Alzheimer and vascular brain disease: Arteriosclerotic atrophy of the brain. [PDF]
, 2015 Alois Alzheimer is best known for his description of neurofibrillary changes in brain neurons of a demented patient, identifying a novel disease, soon named after him by Kraepelin.
Engelhardt, Eliasz, Grinberg, Lea T
core +2 more sources
EMBO Molecular Medicine, 2023 Cognitive decline is a common pathological outcome during aging, with an ill‐defined molecular and cellular basis. In recent years, the concept of inflammaging, defined as a low‐grade inflammation increasing with age, has emerged.
Pierre Lemaitre +10 more
doaj +1 more source
Genetic Defects and Pro-inflammatory Cytokines in Parkinson's Disease
Frontiers in Neurology, 2021 Parkinson's disease (PD) is a movement disorder attributed to the loss of dopaminergic (DA) neurons mainly in the substantia nigra pars compacta. Motor symptoms include resting tremor, rigidity, and bradykinesias, while non-motor symptoms include ...
Albert Frank Magnusen +4 more
doaj +1 more source
A fruitful fly forward : the role of the fly in drug discovery for neurodegeneration [PDF]
, 2014 AD, Alzheimer’s disease; APP, amyloid precursor protein; BBB, blood brain barrier; GFP, green fluorescent protein; HTS, high-throughput screening; HD, Huntington’s disease; LB, Lewy bodies; PD, Parkinson’s disease; PolyQ, Polyglutamine; RNAi, RNA ...
Briffa, Michelle +2 more
core +1 more source