Results 51 to 60 of about 2,638,617 (370)

Simultaneous Matrix Diagonalization for Structural Brain Networks Classification

, 2017
This paper considers the problem of brain disease classification based on connectome data. A connectome is a network representation of a human brain. The typical connectome classification problem is very challenging because of the small sample size and ...
A Kurkumov, A Rohde, A Yeredor, B Fischl, C Cortes, CM Florkowski, CM Tax, F Pedregosa, H Zou, J Rudie, JF Cardoso, L Breiman, P Tichavsky, RS Desikan   +13 more
core   +1 more source

Brain MRI in Parkinson's disease [PDF]

Frontiers in Bioscience, 2014
In this review article, conventional brain MRI and advanced MRI techniques in Parkinson`s disease (PD) are discussed, with emphasis on clinical relevance. Conventional brain MRI sequences generally demonstrate limited abnormalities specific for PD and in clinical practice brain MRI is mainly used to exclude other pathology.
Meijer, F.J.A., Meijer, F.J.A., Goraj, B.M., Goraj, B.M.   +3 more
openaire   +3 more sources

Evaluation of intrafraction couch shifts for proton treatment delivery in head‐and‐neck cancer patients: Toward optimal imaging frequency

Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal, Dario B. Rodrigues, Weiguang Yao, Jason K. Molitoris, Matthew E. Witek, Shifeng Chen   +5 more
wiley   +1 more source

Applications of nanobodies in brain diseases

Frontiers in Immunology, 2022
Nanobodies are antibody fragments derived from camelids, naturally endowed with properties like low molecular weight, high affinity and low immunogenicity, which contribute to their effective use as research tools, but also as diagnostic and therapeutic ...
Fang Zheng, Yucheng Pang, Luyao Li, Yuxing Pang, Jiaxin Zhang, Xinyi Wang, Geert Raes, Geert Raes   +7 more
doaj   +1 more source

Phosphoinositides: Regulators of Nervous System Function in Health and Disease

Frontiers in Molecular Neuroscience, 2019
Phosphoinositides, the seven phosphorylated derivatives of phosphatidylinositol have emerged as regulators of key sub-cellular processes such as membrane transport, cytoskeletal function and plasma membrane signaling in eukaryotic cells.
Padinjat Raghu, Annu Joseph, Harini Krishnan, Pramod Singh, Sankhanil Saha   +4 more
doaj   +1 more source

Widespread sex differences in gene expression and splicing in the adult human brain [PDF]

, 2013
There is strong evidence to show that men and women differ in terms of neurodevelopment, neurochemistry and susceptibility to neurodegenerative and neuropsychiatric disease. The molecular basis of these differences remains unclear. Progress in this field
A Aleman, A Fung, A Subramanian, AA Shabalin, AK Vaags, AM Craig, BG Weinshenker, C Ober, CJ Newschaffer, CS Weickert, D Trabzuni, D Trabzuni, DG Hernandez, DH Skuse, E Heard, E Jazin, F Simunovic, H Skaletsky, HJ Kang, I Cantuti-Castelvetri, I Kato, IN Miller, JB Berletch, JR Gibbs, K Andersen, KP Cosgrove, L Cahill, L Matthews, M Jiang, M Kanehisa, M Kanehisa, MA Nalls, MP Vawter, MT Ross, NL Barbosa-Morais, P Parma, PA McCombe, R Gater, R Schmidt, RA Irizarry, S Amor, S Jamain, S Tang, T Millar, TG Beach, Y Li, Y Li   +46 more
core   +1 more source

Phagocytosis in the Brain: Homeostasis and Disease [PDF]

Frontiers in Immunology, 2019
Microglia are resident macrophages of the central nervous system and significantly contribute to overall brain function by participating in phagocytosis during development, homeostasis, and diseased states. Phagocytosis is a highly complex process that is specialized for the uptake and removal of opsonized and non-opsonized targets, such as pathogens ...
Galloway, DA, Phillips, AEM, Owen, D, Moore, CS   +3 more
openaire   +6 more sources

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Parkinson's disease dementia: a neural networks perspective. [PDF]

, 2015
In the long-term, with progression of the illness, Parkinson's disease dementia affects up to 90% of patients with Parkinson's disease. With increasing life expectancy in western countries, Parkinson's disease dementia is set to become even more ...
Foltynie, T, Gratwicke, J, Jahanshahi, M
core   +1 more source

Brain JNK and metabolic disease [PDF]

Diabetologia, 2020
Obesity, which has long since reached epidemic proportions worldwide, is associated with long-term stress to a variety of organs and results in diseases including type 2 diabetes. In the brain, overnutrition induces hypothalamic stress associated with the activation of several signalling pathways, together with central insulin and leptin resistance ...
Rubén Nogueiras, Rubén Nogueiras, Guadalupe Sabio   +2 more
openaire   +3 more sources