Results 1 to 10 of about 1,182,956 (263)

Investigation of the relationship between iron and high field MRI in healthy and Alzheimer's disease tissue [PDF]

open access: yes
It has been proposed that increased tissue iron concentration, which has been observed in certain regions of the brain in individuals with Alzheimer’s Disease (AD), could provide a marker for diagnosis through detection with MRI.
Finnegan, Mary E.
core  

Urinary Biomarkers of Brain Diseases

open access: yes, 2015
Biomarkers are the measurable changes associated with a physiological or pathophysiological process. Unlike blood, urine is not subject to homeostatic mechanisms.
Gao, Youhe   +3 more
core   +1 more source

The Molecular Pathology of Prion Diseases [PDF]

open access: yes, 2004
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Vassallo, Neville   +2 more
core  

Antimicrobial peptides and complement in neonatal hypoxia-ischemia induced brain damage

open access: yes, 2015
Hypoxic-ischemic encephalopathy (HIE) is a clinical condition in the neonate, resulting from oxygen deprivation around the time of birth. HIE affects 1-5/1000 live births worldwide and is associated with the development of neurological deficits ...
Rocha-Ferreira, E   +5 more
core   +1 more source

Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System

open access: yes, 2019
Background: Diseases of the nervous system are widely considered to be caused by genetic mutations, and they have been shown to share pathogenic genes. Discovering the shared mechanisms of these diseases is useful for designing common treatments. Method:
Wang, Z   +12 more
core   +1 more source

Brain Stimulation and its Role in Neurological Diseases

open access: yes
The growing use of non-invasive brain stimulation in clinical applications reflects its capabilities to transiently modulate cortical excitability, motor and cognitive functions in ways not possible with other techniques. Neurological disorders represent
Zimerman, Maximo   +1 more
core   +1 more source

Iron, copper, zinc, magnesium, and calcium in postmortem brain tissue from schizophrenic patients

open access: yes, 1994
The regional distribution of iron, copper, zinc, magnesium, and calcium in postmortem brain of schizophrenic patients was compared with that of matched controls.
Kruzik, P.   +6 more
core   +1 more source

The sHsp expression signature in the brain and modulation in models of chronic neurodegeneration

open access: yes, 2010
Intrinsic protein folding pathways are modulated by molecular chaperones, such as the diversegroup of heat shock proteins (Hsps). Among these is the small heat shock protein (sHsp)family which in the mammalian genome consists of 10 low molecular weight ...
Quraishe, Shmma
core  

Reconstituting a human brain in animals: a Jewish perspective on human sanctity

open access: yes, 2008
The potential use of stem cells in the treatment of a variety of human diseases has been a major driving force for embryonic stem cell research. Another productive area of research has been the use of human stem cells to reconstitute human organ systems ...
Tendler, Moshe, Loike, John D.
core  

Understanding brain through diseases

open access: yes, 2014
Understanding the causes underlying diseases affecting brain function, mental disabilities and other disorders is a very difficult task that necessitates to deeply trace mechanisms at the basis of the human brain machine, a complex circuitry that ...
Barbara Lombardo, Lucio Pastore
core  

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