Results 11 to 20 of about 1,182,956 (263)

Diagnosis of brain diseases in fusion of neuroimaging modalities using deep learning: A review

Information Fusion, 2023
Brain diseases, including tumors and mental and neurological disorders, seriously threaten the health and well-being of millions of people worldwide. Structural and functional neuroimaging modalities are commonly used by physicians to aid the diagnosis ...
Afshin Shoeibi
exaly   +2 more sources

RNAs in Brain and Heart Diseases [PDF]

International Journal of Molecular Sciences, 2020
In the era of single-cell analysis, one always has to keep in mind the systemic nature of various diseases and how these diseases could be optimally studied.
Dimitris Beis, Inga Zerr, Yvan Devaux, Wolfram Doehner, Fabio Martelli   +4 more
core   +5 more sources

Neuroinflammation and Brain Disease

BMC Neurology, 2023
AbstractStarting from the perspective of an immune-privileged site, our knowledge of the inflammatory processes within the central nervous system has increased rapidly over the last 30 years, leading to a rather puzzling picture today. Of particular interest is the emergence of disease- and injury-specific inflammatory responses within the brain, which
A. Bersano, J. Engele, M.K.E. Schäfer
openaire   +3 more sources

Reprogramming the diseased brain [PDF]

Nature Biotechnology, 2017
Direct conversion of astrocytes to dopamine neurons in vivo offers fresh optimism for the development of improved Parkinson's ...
Dunnett, Stephen, Rosser, Anne
openaire   +2 more sources

Aquaporin and brain diseases [PDF]

Biochimica et Biophysica Acta (BBA) - General Subjects, 2014
The presence of water channel proteins, aquaporins (AQPs), in the brain led to intense research in understanding the underlying roles of each of them under normal conditions and pathological conditions.In this review, we summarize some of the recent knowledge on the 3 main AQPs (AQP1, AQP4 and AQP9), with a special focus on AQP4, the most abundant AQP ...
Jérôme, Badaut, Andrew M, Fukuda, Amandine, Jullienne, Klaus G, Petry   +3 more
openaire   +2 more sources

Bolaamphiphiles as a novel drug delivery system in the treatment of diseases of the brain [PDF]

, 2020
The incidence of central nervous system (CNS) diseases, such as glioblastoma, Alzheimer’s disease and Parkinson’s disease, will increase substantially in the next few decades. However, treatment for diseases of the brain is limited due to the restrictive
Maclatchy, A.
core   +1 more source

Is Alzheimer’s Disease a Liver Disease of the Brain? [PDF]

Journal of Alzheimer's Disease, 2020
Clinical specialization is not only a force for progress, but it has also led to the fragmentation of medical knowledge. The focus of research in the field of Alzheimer’s disease (AD) is neurobiology, while hepatologists focus on liver diseases and lipid specialists on atherosclerosis.
Bassendine, M, Taylor-Robinson, S, Fertleman, M, Khan, M, Neely, D   +4 more
openaire   +3 more sources

"It's a brain disease" [PDF]

Psychiatric Services, 1997
T elling me that I have a brain disease and that I should take medication does not solve my problems. When I was first given the label of “psychotic,” I’m not sure it really mattered to me what had caused it. What I heard was you telling me that I had a chronic disease.
openaire   +2 more sources

Widespread sex differences in gene expression and splicing in the adult human brain. [PDF]

, 2013
There is strong evidence to show that men and women differ in terms of neurodevelopment, neurochemistry and susceptibility to neurodegenerative and neuropsychiatric disease. The molecular basis of these differences remains unclear. Progress in this field
Ramasamy, Adaikalavan, Ryten, Mina, Ramasamy, A, Smith, C, Ryten, M, Trabzuni, D, Walker, R, Smith, Colin, Smith, C; id_orcid, Trabzuni, Daniah, Imran, S, Weale, M, Hardy, John, ?, ?, Weale, Michael E, Hardy, J, North American Brain Expression Consortium, Weale, ME, Imran, Sabaena, Walker, Robert   +19 more
core   +1 more source

Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation. [PDF]

, 2014
Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development of neuroinflammatory disorders ...
Susanne MA van der Pol, Male, David K, Cerutti, Camilla, Michael, G.J., Dongsheng Wu, van der Pol, SM, Sharrack, B, Romero, I.A., Baker, D., Michael, Gregory J, Simpson, Julie E., Cerutti, C., Simpson, J.E., Lopez-Ramirez, Miguel A., David Baker, Romero, IA, Wu, D.S., de Vries, H.E., Baker, David, King-Robson, J., Basil Sharrack, Simpson, Julie E, Michael, GJ, Wu, Dongsheng, van der Pol, Susanne M A, Hirst, Mark C, Julie E Simpson, Ignacio A Romero, Pryce, Gareth, Baker, D, Gregory J Michael, de Vries, Helga E, Romero, Ignacio A., Hirst, MC, King-Robson, Josh, de Vries, HE, Lopez-Ramirez, Alejandro, Mark C Hirst, David K Male, Male, DK, de Vries, Helga E., Gareth Pryce, Josh King-Robson, Camilla Cerutti, van der Pol, SMA, Romero, Ignacio A, van der Pol, S.M.A., Lopez-Ramirez, Miguel A, Male, D.K., Male, David K., Sharrack, B., King-Robson, J, van der Pol, Susanne M. A., Wu, D, Simpson, JE, Lopez-Ramirez, MA, Miguel A Lopez-Ramirez, Hirst, M.C., van der Pol, Susanne Ma, Cerutti, C, Helga E de Vries, Pryce, G, Pryce, G., Hirst, Mark C., Sharrack, Basil, Michael, Gregory J., Lopez-Ramirez, M.A.   +66 more
core   +1 more source