Results 31 to 40 of about 4,808,098 (303)

Automated Identification of Multiple Findings on Brain MRI for Improving Scan Acquisition and Interpretation Workflows: A Systematic Review

Diagnostics, 2022
We conducted a systematic review of the current status of machine learning (ML) algorithms’ ability to identify multiple brain diseases, and we evaluated their applicability for improving existing scan acquisition and interpretation workflows.
Kaining Sheng, Cecilie Mørck Offersen, Jon Middleton, Jonathan Frederik Carlsen, Thomas Clement Truelsen, Akshay Pai, Jacob Johansen, Michael Bachmann Nielsen   +7 more
doaj   +1 more source

Glia: the fulcrum of brain diseases [PDF]

Cell Death & Differentiation, 2007
Neuroglia represented by astrocytes, oligodendrocytes and microglial cells provide for numerous vital functions. Glial cells shape the micro-architecture of the brain matter; they are involved in information transfer by virtue of numerous plasmalemmal receptors and channels; they receive synaptic inputs; they are able to release 'glio'transmitters and ...
Giaume, C., Kirchhoff, F., Matute, C., Reichenbach, A., Verkhratsky, A.; id_orcid 0000-0003-2592-9898   +4 more
openaire   +3 more sources

Widespread sex differences in gene expression and splicing in the adult human brain. [PDF]

, 2013
There is strong evidence to show that men and women differ in terms of neurodevelopment, neurochemistry and susceptibility to neurodegenerative and neuropsychiatric disease. The molecular basis of these differences remains unclear. Progress in this field
Ramasamy, Adaikalavan, Ryten, Mina, Ramasamy, A, Smith, C, Ryten, M, Trabzuni, D, Walker, R, Smith, Colin, Smith, C; id_orcid, Trabzuni, Daniah, Imran, S, Weale, M, Hardy, John, ?, ?, Weale, Michael E, Hardy, J, North American Brain Expression Consortium, Weale, ME, Imran, Sabaena, Walker, Robert   +19 more
core   +1 more source

KCNB1 Mutations in Epileptic Encephalopathy

Pediatric Neurology Briefs, 2014
Researchers at Scripps Research Institute, San Diego, and other centers in California; Johns Hopkins, Baltimore; Vanderbilt University, TN; and Northwestern University Feinberg School of Medicine, Chicago, IL; searched for de novo mutations in a family ...
J Gordon Millichap, John J Millichap
doaj   +1 more source

Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles

Cells, 2020
The blood–brain barrier (BBB) is one of the most complex and selective barriers in the human organism. Its role is to protect the brain and preserve the homeostasis of the central nervous system (CNS).
Julien Saint-Pol, Fabien Gosselet, Sophie Duban-Deweer, Gwënaël Pottiez, Yannis Karamanos   +4 more
doaj   +1 more source

Does the functional polymorphism-1562C/T of MMP-9 gene influence brain disorders?

Frontiers in Cellular Neuroscience, 2023
Metalloproteinase-9 (MMP-9) is one of the most strongly expressed matrix metalloproteinases (MMPs) in the brain. The MMP-9 activity in the brain is strictly regulated, and any disruptions in this regulation contribute to a development of many disorders ...
Sylwia Pabian-Jewuła, Marcin Rylski
doaj   +1 more source

Brain endothelial miR-146a negatively modulates T-cell adhesion through repressing multiple targets to inhibit NF-κB activation. [PDF]

, 2014
Pro-inflammatory cytokine-induced activation of nuclear factor, NF-κB has an important role in leukocyte adhesion to, and subsequent migration across, brain endothelial cells (BECs), which is crucial for the development of neuroinflammatory disorders ...
Susanne MA van der Pol, Male, David K, Cerutti, Camilla, Michael, G.J., Dongsheng Wu, van der Pol, SM, Sharrack, B, Romero, I.A., Baker, D., Michael, Gregory J, Simpson, Julie E., Cerutti, C., Simpson, J.E., Lopez-Ramirez, Miguel A., David Baker, Romero, IA, Wu, D.S., de Vries, H.E., Baker, David, King-Robson, J., Basil Sharrack, Simpson, Julie E, Michael, GJ, Wu, Dongsheng, van der Pol, Susanne M A, Hirst, Mark C, Julie E Simpson, Ignacio A Romero, Pryce, Gareth, Baker, D, Gregory J Michael, de Vries, Helga E, Romero, Ignacio A., Hirst, MC, King-Robson, Josh, de Vries, HE, Lopez-Ramirez, Alejandro, Mark C Hirst, David K Male, Male, DK, de Vries, Helga E., Gareth Pryce, Josh King-Robson, Camilla Cerutti, van der Pol, SMA, Romero, Ignacio A, van der Pol, S.M.A., Lopez-Ramirez, Miguel A, Male, D.K., Male, David K., Sharrack, B., King-Robson, J, van der Pol, Susanne M. A., Wu, D, Simpson, JE, Lopez-Ramirez, MA, Miguel A Lopez-Ramirez, Hirst, M.C., van der Pol, Susanne Ma, Cerutti, C, Helga E de Vries, Pryce, G, Pryce, G., Hirst, Mark C., Sharrack, Basil, Michael, Gregory J., Lopez-Ramirez, M.A.   +66 more
core   +1 more source

Tuberous Sclerosis Complex and Arachnoid Cysts

Pediatric Neurology Briefs, 2014
Investigators at the Massachusetts General Hospital, Boston, MA, and Universitat Autonoma de Barcelona, Spain, assessed the prevalence and characteristics of arachnoid cysts in a cohort of 220 patients with tuberous sclerosis complex (TSC).
J Gordon Millichap, John J Millichap
doaj   +1 more source

A Geographic Approach to Measuring and Organising Affordable Medical and Therapeutic Tourism for People with Dementia

Quaestiones Geographicae, 2020
The article covers the geographical features of the organisation of medical tourism for a group of the world's population suffering from a brain disease – dementia.
Semenova Zoya A., Chistobaev Anatoliy I., Dildina Valeriya P.   +2 more
doaj   +1 more source

Analysis of clinical phenotype and gene variation characteristics of potassium channel gene variation in infants with epileptic encephalopathy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Objective To analyze and summarize the clinical and genetic characteristics of potassium channel gene variation in infant epileptic encephalopathy (EE).
XU Rong, NING Ze⁃shu, KANG Qing⁃yun, CHEN Bo, LIAO Hong⁃mei, YANG Li⁃ming, WU Li⁃wen   +6 more
doaj   +1 more source