Results 111 to 120 of about 12,470,437 (381)

Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in alzheimer’s disease and parkinson’s disease [PDF]

open access: yes, 2017
Alzheimer's disease and Parkinson's disease are two common neurodegenerative diseases of the elderly people that have devastating effects in terms of morbidity and mortality.
Chakrabarti, S.   +3 more
core   +3 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Dendritic cells in brain diseases

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2016
Authors receive financial support by the European Community (FP7-PEOPLE-2013-ITN-n°07962, supporting M.G.; the ERA-NET program PRI-PIMNEU-2011-1342; and FP7-HEALTH-F2-2011-n°278850); the Werner-Otto-Stiftung (17/86, supporting S.B.); the University of Hamburg (NWF-15/07); and the Spanish Ministry of Economy MINECO (SAF2014-56279)
Peter Ludewig   +7 more
openaire   +5 more sources

Interview with the Coordinator Prof. Giuseppe Di Giovanni, University of Malta, Department of Physiology and Biochemistry [PDF]

open access: yes, 2015
Interview with the Coordinator of the Malta Neuroscience Network Programme, Prof. Giuseppe Di Giovanni regarding the Malta Neuroscience Net- work. "With the creation of the Malta Neuroscience Network, we will be keeping up with the most important ...
Di Giovanni, Giuseppe
core  

Electrical Stimulation Modulates High γ Activity and Human Memory Performance. [PDF]

open access: yes, 2018
Direct electrical stimulation of the brain has emerged as a powerful treatment for multiple neurological diseases, and as a potential technique to enhance human cognition.
Berry, Brent M.   +17 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Computer discrimination between diseases of the brain based on MR image features [PDF]

open access: yes, 2003
No description ...
du Boulay, Benedict   +7 more
core   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

AMPK in the central nervous system: physiological roles and pathological implications [PDF]

open access: yes, 2016
5′ AMP-activated protein kinase (AMPK) is considered the master metabolic regulator in all eukaryotes, as it maintains cellular energy homeostasis in a variety of tissues, including the brain.
Fioramonti, Marco   +6 more
core   +1 more source

Actions of Brain-Derived Neurotrophin Factor in the Neurogenesis and Neuronal Function, and Its Involvement in the Pathophysiology of Brain Diseases

open access: yesInternational Journal of Molecular Sciences, 2018
It is well known that brain-derived neurotrophic factor, BDNF, has an important role in a variety of neuronal aspects, such as differentiation, maturation, and synaptic function in the central nervous system (CNS).
T. Numakawa, Haruki Odaka, N. Adachi
semanticscholar   +1 more source

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