Results 151 to 160 of about 12,470,437 (381)
FEBS Open Bio, EarlyView.Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei +7 more
wiley +1 more source
Urinary Biomarkers of Brain Diseases
Genomics, Proteomics & Bioinformatics, 2015 Abstract Biomarkers are the measurable changes associated with a physiological or pathophysiological process. Unlike blood, urine is not subject to homeostatic mechanisms. Therefore, greater fluctuations could occur in urine than in blood, better reflecting the changes in human body.
Youhe Gao, Youhe Gao, Manxia An
openaire +3 more sources
Symptoms and Etiologies of Alice in Wonderland Syndrome
Pediatric Neurology Briefs, 2014 Investigators from Children's Hospital of Philadelphia, PA, conducted a retrospective chart review of 48 children (average age at presentation 8.1 yrs, range 5-14 yrs; 73% male) diagnosed with “Alice in Wonderland” syndrome (AWS) or “Alice in Wonderland”-
J Gordon Millichap, John J Millichap
doaj +1 more source
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran +3 more
wiley +1 more source
Resistome phylodynamics of multidrug-resistant Shigella isolated from diarrheal patients
Microbiology SpectrumMulti-drug resistance (MDR) in Shigella continues to pose a significant public health challenge, particularly in developing countries. Recent advances in genomics strengthen the surveillance of MDR-pathogens and antimicrobial resistance (AMR) mediators ...
Asaduzzaman Asad +8 more
doaj +1 more source
Congenital Myasthenic Syndrome with Agrin Mutations
Pediatric Neurology Briefs, 2014 Investigators at Newcastle University, UK, and Hopitaux de Paris, France, report 5 patients from 3 unrelated families with a strikingly homogeneous clinical entity combining congenital myasthenia with distal muscle weakness and atrophy resembling a ...
J Gordon Millichap, John J Millichap
doaj +1 more source
Use of Polyamidoamine Dendrimers in Brain Diseases
Molecules, 2018 Polyamidoamine (PAMAM) dendrimers are one of the smallest and most precise nanomolecules available today, which have promising applications for the treatment of brain diseases. Each aspect of the dendrimer (core, size or generation, size of cavities, and
Maria Florendo +6 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal +2 more
wiley +1 more source
Multiple Sclerosis and Seizure Prevalence
Pediatric Neurology Briefs, 2014 Investigators from Oslo University Hospital and other centers in Norway studied changes in the prevalence and incidence of multiple sclerosis (MS) in Vestfold County, Norway, in the period 1983-2003.
J Gordon Millichap, John J Millichap
doaj +1 more source