Results 171 to 180 of about 1,760,110 (357)

Aging‐Driven Blood–Brain Barrier Dysfunction and Its Impact on CNS Cancer Susceptibility: A Comprehensive Narrative Review

Aging and Cancer, EarlyView.
Aging weakens the blood–brain barrier (BBB), increasing susceptibility to CNS cancers and complicating treatment. This review examines BBB deterioration, its impact on drug delivery, and potential interventions like targeting neuroinflammation and advanced therapies.
Quang La, Aiman Baloch, David F. Lo
wiley   +1 more source

Clinical pharmacology of generic topiramate and its role in the treatment of epilepsy

Медицинский совет, 2013
Epilepsy is one of the most common neurological diseases and a relevant medical and social problem of the modern society. About 1% of people from the general population are considered to have had at least one epileptic seizure during their life.
S. A. Babanov
doaj   +1 more source

Pyogenic Infective Diseases of the Brain and Spinal Cord; Meningitis, Abscess of the Brain, Infective Sinus Thrombosis [PDF]

, 1894
NULL AUTHOR_ID
openalex   +1 more source

A network aggregation model for the dynamics and treatment of neurodegenerative diseases at the brain scale [PDF]

arXiv
Neurodegenerative diseases are associated with the assembly of specific proteins into oligomers and fibrillar aggregates. At the brain scale, these protein assemblies can diffuse through the brain and seed other regions, creating an autocatalytic protein progression.
arxiv  

Abscess in the Brain Resulting from Disease of the Ear [PDF]

, 1887
Thomas Barr
openalex   +1 more source

Assessing proton plans with three different beam delivery systems versus photon plans for head and neck tumors

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To compare plan quality among photon volumetric modulated arc therapy (VMAT) and intensity‐modulated proton therapy (IMPT) with robustness using three different proton beam delivery systems with various spot size (σ) ranges: cyclotron‐generated proton beams (CPBs) (σ: 2.7–7.0 mm), linear accelerator proton beams (LPBs) (σ: 2.9–5.5 mm),
Tara Gray, Chieh‐Wen Liu, Saeed Ahmed, Anna Maria Kolano, Jeremy Donaghue, Shlomo Koyfman, Neil Woody, Shauna R. Campbell, Jonathan B. Farr, Ping Xia   +9 more
wiley   +1 more source

Identification of the clinical and genetic characteristics of gliomas with gene fusions by integrated genomic and transcriptomic analysis

European Journal of Medical Research
The identification of oncogenic gene fusions in diffuse gliomas may serve as potential therapeutic targets and prognostic indicators, representing a novel strategy for treating gliomas consistent with the principles of personalized medicine.
Guo-zhong Yi, Hua-yang Zhang, Tian-shi Que, Shan-qiang Qu, Zhi-yong Li, Song-tao Qi, Wen-yan Feng, Guang-long Huang   +7 more
doaj   +1 more source

The effect of multi‐leaf collimator leaf width on VMAT treatment plan quality

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The advent of volumetric modulated arc therapy (VMAT) in radiotherapy has made it one of the most commonly used techniques in clinical practice. VMAT is the delivery of intensity modulated radiation therapy (IMRT) while the gantry is in motion, and existing literature has shown it has decreased treatment delivery times and the ...
Gregory Sadharanu Peiris, Brendan Whelan, Nicholas Hardcastle, Suzie Lynn Sheehy   +3 more
wiley   +1 more source

T2‐weighted imaging of rectal cancer using a 3D fast spin echo sequence with and without deep learning reconstruction: A reader study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To compare image quality and clinical utility of a T2‐weighted (T2W) 3‐dimensional (3D) fast spin echo (FSE) sequence using deep learning reconstruction (DLR) versus conventional reconstruction for rectal magnetic resonance imaging (MRI).
Dan Nguyen, Sarah Palmquist, Ken‐Pin Hwang, Jingfei Ma, Usama Salem, Jia Sun, Xinzeng Wang, Jong Bum Son, Randy Ernst, Peng Wei, Harmeet Kaur, Nir Stanietzky   +11 more
wiley   +1 more source

Oxytocin attenuates hypothalamic injury-induced cognitive dysfunction by inhibiting hippocampal ERK signaling and Aβ deposition

Translational Psychiatry
In clinical settings, tumor compression, trauma, surgical injury, and other types of injury can cause hypothalamic damage, resulting in various types of hypothalamic dysfunction.
Guangsen Wu, Yichao Ou, Zhanpeng Feng, Zhiwei Xiong, Kai Li, Mengjie Che, Songtao Qi, Mingfeng Zhou   +7 more
doaj   +1 more source