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1986
Current concepts on the development of brain edema are briefly reviewed. The common classification into vasogenic and cytotoxic edema is a simplification and does not cover all types of edema. Alternative routes of edema resolution are discussed. More basic data on the mechanisms of development and regression of brain edema are needed before more ...
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Current concepts on the development of brain edema are briefly reviewed. The common classification into vasogenic and cytotoxic edema is a simplification and does not cover all types of edema. Alternative routes of edema resolution are discussed. More basic data on the mechanisms of development and regression of brain edema are needed before more ...
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Blood–brain barrier and brain edema
2012Abstract The function of the blood–brain barrier (BBB) continues to be a diagnostic and therapeutic challenge for physicians treating patients with central nervous system (CNS) malignancies. Despite its physiological importance, only a few clinical studies have specifically addressed the role of the BBB in the biology of brain tumors.
Michael Platten, Wolfgang Wick
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Pathophysiological aspects of brain edema
Acta Neuropathologica, 1972Two mayor types of brain edema, related to two different pathomechanisms, can be recognized: 1) cytotoxic type-where the main feature is the swelling of cellular elements of brain parenchyma and 2) vasogenic type-where an increased vascular permeability leading to accumulation of edema fluid in the extracellular spaces plays the principal role. In this
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1997
Vasogenic edema is the most common type of brain edema. It is seen in clinical conditions where the vascular endothelial cells in the brain are selectively injured such as in acute hypertension or lead intoxication or where their function is modified by an infectious process such as in meningitis, encephalitis, and abscess.
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Vasogenic edema is the most common type of brain edema. It is seen in clinical conditions where the vascular endothelial cells in the brain are selectively injured such as in acute hypertension or lead intoxication or where their function is modified by an infectious process such as in meningitis, encephalitis, and abscess.
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Brain edema – a new classification
Medical Hypotheses, 2003Brain edema is a reaction to any brain injury and can be the first stage in the beginning of intracranial hypertension. This paper puts forth a modern classification of brain edema types, based on a etiopathogenic interpretation. The hydroelectrolitic and/or proteinic buildup can occur within cells and/or in the extracellular space and differentiates ...
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The pathophysiology of experimental brain edema
Neurosurgical Review, 1989In the following, the pathophysiology of brain edema is reviewed, using edema related to intracerebral tumor development as a typical example of the vasogenic type of edema and brain swelling related to stroke as an example of cytotoxic type of edema.
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Pharmacologic management of brain edema
Current Treatment Options in Neurology, 2008Cerebral edema is an intrinsic response to a variety of structural and metabolic insults. It is a major contributing factor in the development of intracranial hypertension and brain herniation, underscoring the need for early identification through an integration of clinical and neuroimaging findings, followed by timely institution of measures to ...
Robert Stevens +3 more
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Brain Edema and the Blood-Brain Barrier
1997This chapter explains basic concepts related to brain edema and the blood–brain barrier (BBB). Brain edema is defined as an increase in brain tissue water content. Because the increase occurs within a closed cranium and is accompanied by brain swelling, edema often produces a clinical syndrome manifested by intracranial hypertension, papilledema, and ...
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1987
Among the cerebrovascular occlusive disorders, brain edema following brain ischemia, in which the brain volume increases and the brain suffers herniation, is the most common cause of death. Since, as medicions, we must treat the ischemic brain and try to prevent brain edema, a complete understanding of the pathogenesis of brain edema is extremely ...
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Among the cerebrovascular occlusive disorders, brain edema following brain ischemia, in which the brain volume increases and the brain suffers herniation, is the most common cause of death. Since, as medicions, we must treat the ischemic brain and try to prevent brain edema, a complete understanding of the pathogenesis of brain edema is extremely ...
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Therapy of Ischemic Brain Edema
European Neurology, 1978With corticosteroids and diuretics, glycerol treatment may be an effective therapy of early edema accompanying focal brain ischemia. The suggested regimen for intravenous infusion is 500 ml of 10% glycerol solution during at least 2 h, twice a day, starting as soon as possible after stroke onset and continuing thereafter for 5--7 days.
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