Results 151 to 160 of about 244,035 (260)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

The Quantum Brain: The Untold Story of Docosahexaenoic Acid's Role in Brain Evolution, Biophysics, and Cognition. [PDF]

Int J Mol Sci
Crawford MA, Horn LA, Brenna T, Broadhurst CL, Dyall SC, Johnson M, Schmidt WF, Sinclair AJ, Thabet M, Wang Y.   +9 more
europepmc   +1 more source

Human brain evolution: Emerging roles for regulatory DNA and RNA. [PDF]

Curr Opin Neurobiol, 2021
Liu J, Mosti F, Silver DL.
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Body Cognition and Self-Domestication in Human Evolution

Frontiers in Psychology, 2019
Emiliano Bruner, Ben T. Gleeson
doaj   +1 more source

The Placental Steroid Hypothesis of Human Brain Evolution. [PDF]

Evol Anthropol
Tsompanidis A, Burton GJ, Baron-Cohen S, Dunbar RIM.   +3 more
europepmc   +1 more source

Tandemly repeated NBPF HOR copies (Olduvai triplets): Possible impact on human brain evolution. [PDF]

Life Sci Alliance, 2023
Glunčić M, Vlahović I, Rosandić M, Paar V.   +3 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

So Fragile, So Human: Noncoding DNA Regions Orchestrating Gene Expression Involved in Neurodevelopmental Disorders and in Human Brain Evolution. [PDF]

Int J Mol Sci
Marenco C, Pozzolini G, Casciaro M, Morales M, Barone C, Morciano D, Barillari C, Zakirova E, Antoniazzi G, Lahoud T, Mosconi F, Cabassi D, Noonan JP, Bacchelli E, Nicolis SK.   +14 more
europepmc   +1 more source

Convergent mosaic brain evolution is associated with the evolution of novel electrosensory systems in teleost fishes. [PDF]

Elife, 2022
Schumacher EL, Carlson BA.
europepmc   +1 more source