Results 141 to 150 of about 244,035 (260)

Tandem repeats in human brain evolution and disease susceptibility. [PDF]

Mol Cells
Lee H, An JY.
europepmc   +1 more source

SIRT6 Through the Brain Evolution, Development, and Aging. [PDF]

Front Aging Neurosci, 2021
Garcia-Venzor A, Toiber D.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Human gut microbiota and brain evolution. [PDF]

Proc Natl Acad Sci U S A
Moeller AH.
europepmc   +1 more source

Retrotransposons as Drivers of Mammalian Brain Evolution. [PDF]

Life (Basel), 2021
Ferrari R, Grandi N, Tramontano E, Dieci G.   +3 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

The relative withdrawal of GFAP-An essential component of brain evolution. [PDF]

Front Neuroanat
Kálmán M.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Impact of intermittent lead exposure on hominid brain evolution. [PDF]

Sci Adv
Joannes-Boyau R, de Souza JS, Arora M, Austin C, Westaway K, Moffat I, Wang W, Liao W, Zhang Y, Adams JW, Fiorenza L, Dérognat F, Moncel MH, Schwartz GT, Bailey M, Dos Santos FF, Guardia GDA, Mercuri RLV, Galante PAF, Martins AMA, Tsu BL, Barnes CA, Yates J, Petroski LP, Sanchez-Sanchez SM, Oviedo J, Herai RH, Lemos B, Tonge M, Muotri AR.   +29 more
europepmc   +1 more source

Cerebral cortical processing time is elongated in human brain evolution. [PDF]

Sci Rep, 2022
Itoh K, Konoike N, Nejime M, Iwaoki H, Igarashi H, Hirata S, Nakamura K.   +6 more
europepmc   +1 more source