Results 191 to 200 of about 192,387 (282)

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Incidental Diagnosis of Fahr's Disease Following Severe Traumatic Brain Injury: A Case Report. [PDF]

Clin Case Rep
Ebrahimi H, Holakoo A, Hejazian SE, Ahmadian H, Zohrevand AH, Sharifzadeh M.   +5 more
europepmc   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Trends in the use of opioid and non-opioid analgesics after TBI with and without polytrauma. [PDF]

Trauma Surg Acute Care Open
Medvecz AJ, Maiga AW, Dusetzina S, Guillamondegui OD, Wiese AD.   +4 more
europepmc   +1 more source

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Experiences of Home Care Team Members and Family Caregivers in Addressing the Care Needs of Patients with Severe Traumatic Brain Injury During the Post-discharge Period. [PDF]

Iran J Nurs Midwifery Res
Mohamadirizi S, Irajpour A, Mahaabadi A, Aminmansour B, Alimohammadi N.   +4 more
europepmc   +1 more source

Robotic Needle Steering for Percutaneous Interventions: Sensing, Modeling, and Control

Advanced Intelligent Systems, EarlyView.
This review examines recent advances in robotic needle steering for percutaneous interventions, highlighting closed‐loop sensing, physics‐informed tissue‐needle interaction modeling, and real‐time trajectory planning and control. It synthesizes innovations in deep learning, fiber‐optic feedback, and adaptive control strategies, and outlines emerging ...
Fangjiao Zhao, Ruixue Xu, Wujun Zhao, Xi‐Ming Sun, Yu Sun, Changsheng Dai   +5 more
wiley   +1 more source

"Talk and die" syndrome, a tragedy in traumatic brain injury: a cohort study. [PDF]

J Med Case Rep
Arnaout MM, Makia MA, Bessar AA, ElSheikh MO.   +3 more
europepmc   +1 more source

Centimeter‐Scale Magneto‐Reconfigurable Parallel Robots: A Grassmann Line Geometry Synthesis Framework for Multitask Adaptation Using Magneto‐Connected Part Library

Advanced Intelligent Systems, EarlyView.
A low‐cost, Lego‐like magneto‐connected part library is proposed, capable of rapidly assembling, disassembling, and reassembling compact, centimeter‐scale parallel robots with various motion types, balancing structural rigidity and reconfiguration agility.
Yunong Li, Bin Zhu, Wenchao Yue, Zhiwei Fang, Xiao Xiao, Hongliang Ren   +5 more
wiley   +1 more source